Campbell Biology
Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Chapter 17.3, Problem 1CC

There are about 20,000 human protein-coding genes. How can human cells make 75,000-100,000 different proteins?

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There are about 20,000 human protein-coding genes. Howcan human cells make 75,000–100,000 different proteins?
Do most cells contain complete copies of an organism’s DNA? Do most cells express all of the genes contained in their DNA?
Based on our modern understanding, what revisions are necessary to the original one-gene / one-enzyme hypothesis? (Check all that apply.) Alternative splicing allows one gene to encode multiple polypeptides. Some genes encode RNAs, not enzymes. Some genes encode lipids, not enzymes. Some genes encode polypeptides that are not enzymes, such as structural proteins. Proteins as functional units may be composed of several polypeptides, so genes may encode just one polypeptide within a larger protein. Enzymes are not encoded by genes after all — they are constructed through separate biochemical processes.

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