Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Textbook Question
Chapter 13.1, Problem 1CC
MAKE CONNECTIONS → Using what you know of gene expression in a cell, explain what causes the traits of parents (such as hair color) to show up in their offspring. (See Concept 5.5.)
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4e. You also study the expression of 3 different mutants for this gene. For each mutant answer the
following:
Does this mutation change the sequence of the protein produced? Why or why not?
If it does change the sequence of protein be sure to write out the new sequence.
If it does not change the protein sequence, what effect (if any) would you expect it
to have on expression of the gene?
1
20
ORI
40
60
5'...TTCGAGCTCTCGTCGTCGAGATACGCGATGATATTACTGGTAATATGGGGATGCACTATC...3'
3' ...AAGCTCGAGAGCAGCAGCTCTATGCGCTACTATAATGACCATTATACCCCTACGTGATAG...5'
*
promoter
4e. You also study the expression of 3 different mutants for this gene. For each mutant answer the
following:
Does this mutation change the sequence of the protein produced? Why or why not?
If it does change the sequence of protein be sure to write out the new sequence.
If it does not change the protein sequence, what effect (if any) would you expect it
to have on expression of the gene?
1
20
ORI
40
60
5'..TTCGAGCTCTCGTCGTCGAGATACGCGATGATATTACTGGTAATATGGGGATGCACTATC...3’
3'...AAGCTCGAGAGCAGCAGCTCTATGCGCTACTATAATGACCATTATACCCCTACGTGATAG...5’
promoter
i. Mutant A has a single base pair substitution with the T/A being replaced with C/G base pair at
position 35 (position denoted by the * in the sequence above).
ii. Mutant B has a 2 G/C pairs inserted between position 19 and 20 (position denoted by the ^ in
the sequence above).
. What is an enhanceosome? Why could a mutation in anyone of the enhanceosome proteins severely reduce thetranscription rate?
Chapter 13 Solutions
Campbell Biology
Ch. 13.1 - MAKE CONNECTIONS Using what you know of gene...Ch. 13.1 - Prob. 2CCCh. 13.1 - WHATIF? A horticulturalist breeds orchids, trying...Ch. 13.2 - MAKE CONNECTIONS In Figure 13.4. how many DNA...Ch. 13.2 - VISUAL SKILLS In The karyotype shown in Figuro...Ch. 13.2 - Prob. 3CCCh. 13.2 - WHAT IF? A certain eukaryote lives as a...Ch. 13.3 - MAKE CONNECTIONS Comparc tho chromosomes in a...Ch. 13.3 - WHAT IF? After the synaptonemal complex...Ch. 13.4 - What is the original source of Variation among the...
Ch. 13.4 - The diploid number for fruit flies is 8, and the...Ch. 13.4 - Prob. 3CCCh. 13 - Explain why human offifuing resemble their parents...Ch. 13 - Prob. 13.2CRCh. 13 - Prob. 13.3CRCh. 13 - Prob. 13.4CRCh. 13 - A human cell containing 22 autosomes.and a Y...Ch. 13 - The two homologs of a pair move toward opposite...Ch. 13 - Meiosis II is similar to mitosis in that (A)...Ch. 13 - Prob. 4TYUCh. 13 - If we continue to follow the cell lineage from...Ch. 13 - DRAW IT The diagram shows a cell in meiosis. (a)...Ch. 13 - Explain how you can tell that the cell in question...Ch. 13 - EVOLUTION CONNECTION Many species can reproduce...Ch. 13 - SCIENTIFIC INQUIRY The diagram in quest ion 6...Ch. 13 - Prob. 10TYUCh. 13 - SYNTHESIZE YOUR KNOWLEDGE For selected answers,...
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- • All nuclei in multicellular animals' cells have the exact identical genes. However, the sets of genes transcribed in a cell varies dramatically from one cell to the next. Explain how gene transcription patterns are regulated in various cell types.• Describe one type of gene regulation that occurs after transcription is completed.arrow_forwardWHAT IF? Suppose X-rays caused a sequence changein the TATA box of a particular gene’s promoter. Howwould that affect transcription of the gene? (SeeFigure 17.9.)arrow_forwardVISUALIZE Sketch a roughly cuboidal cell preparing to divide. Indicate the orientation of the preprophase band and the site where the new cell walls of the daughter cells will form.arrow_forward
- Please answer fast In one organism it was found out that there are 200,000 proteins while in a different study we found that there are 50,000 genes what is the phenomenon this organism is experiencing?arrow_forwardQ. The nuclear membrane disintegrates late in prophase of mitosis in most eukaryotic cells. Once the membrane is reformed in telophase in a daughter cell, several components of gene expression might therefore be “caught” out in the cytoplasm when they would otherwise only ever be found inside the nucleus. Consider where the following components of gene expression are made and where they function. Which component is normally never found in the cytoplasm outside the nucleus? spliced intron RNA polymerase snRNA DNA polymerase A. 1, 2 and 3 B. 1 and 3 C. 2 and 4 D. 4 only E. All of 1, 2, 3 & 4 are correctarrow_forward. Early in development, most human cells turn off expression of an essential component of telomerase, the enzyme responsible for addition of telomere repeat sequences (5’-TTAGGG) to the ends of chromosomes. Thus, as our cells proliferate their telomeres get shorter and shorter, but are normally not lost over the course of a lifetime. If cells are removed from the body and grown in culture, however they ultimately enter a state of replicative senescence and stop dividing when their telomeres get too short. By contrast, most human tumor cells express active telomerase, allowing them to maintain their telomeres and grow beyond the normal limit imposed by senescence - good for them, bad for us. Anticipating a universal cure for cancer, you set up a company to screen chemical ‘libraries’ for telomerase inhibitors. The company share price takes a dive, however, when a rival group generates a strain of telomerase-knockout mice. These mice breed happily for several generations, but…arrow_forward
- How does position effect influence gene expression? 1 | The movement of the genetic material on the chromosome by inversions or translocations may place a coding sequence near a new regulatory region, thus activating the expression of the gene. The movement of the gene may place it into a region that is highly condensed (heterochromatin). The movement of a gene may remove it from its normal promoter, thus silencing the gene. O All of the above answers are correctarrow_forward5. This diagram illustrates regulation of the Pitx-1 gene, which is expressed in various cell types • during certain stages of animal embryonic development. Answer the questions that follow: Promoter Coding Region Pelvis Olfactory Jaw Regulatory Segments ("Switches") a. Which portion of this sequence gets transcribed and translated into a protein? b. Which portion of this sequence underwent a deletion mutation in certain species of freshwater stickleback fish? Did that mutation have an impact on the amino acid sequence of the protein, when it was expressed? С. d. If this switch underwent the same mutation in a turtle embryo, how would the turtle's phenotype be impacted? е. Would this phenotypic change in the turtle likely be adaptive? Briefly explain.arrow_forwardWhy is the control of gene expression important for cells? Choose one: It ensures the accurate replication of DNA. It prevents mutations from occurring during transcription and translation. • It regulates the synthesis of proteins necessary for cellular functions.arrow_forward
- Describe the ways in which gene expression is regulated Must include: • Transcription factors• Histone acetylation• DNA methylationarrow_forwardExploring Further: The table below outlines the stpes in eukaryotic gene expressions. Briefly summarize each steps given. Gene Expression Steps Molecules Involved Summary What molecules and proteins are What happens during this involved in this steps? step? Transcription RNA Splicing MRNA Transport Translation Protein Processingarrow_forwardQuick help!!! Answer the following questions Only in cell biology 1. A. Discuss the roles of two main types of genes that are critical in cancer? B. What is the difference between a totipotent and a pluripotent stem cell? Give an example to each.arrow_forward
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