Why is it important that the hexokinase reaction have a large negative deltaG? Would the cell be able to generate/store energy if the deltaG were close to zero? The GAPDH reaction uses an active site cysteine to catalyze the reaction. How would replacing the cysteine by serine affect the

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter27: Metabolic Integration And Organ Specialization
Section: Chapter Questions
Problem 20P: Figure 27.3 illustrates the response of R (ATP-regenerating) and U (ATP-utilizing) enzymes to energy...
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Why is it important that the hexokinase reaction have a large negative deltaG? Would the cell be able to generate/store energy if the deltaG were close to zero? The GAPDH reaction uses an active site cysteine to catalyze the reaction. How would replacing the cysteine by serine affect the reaction? Why do kinases require magnesium to function well?
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