While furthering your studies of iocane powder you determine that a ceular enzyme, iocase will degrade it. Under normal conditions, iocase shows km 0f 1.85 uM and a kcat of 76. The drug sildenafil was found to have no effect on the km of iocanse yet the kcat was found to drop 58 minutes^-1, when the drug was added and no other changes were made in the reaction conditions. What can be inferred from this data? (remember kcat = vmax/et)Sildenafil acts as an uncompetitive inhibitor of iocanse Sildenafil acts as a noncompetitive inhibitor of iocanse The effect of sildenafil could be countered by adding more iocane to the reactionThe y-intercept of the sildenafil inhibited iocanse would appear to be lower on a Lineweaver burke plot as compared to uninhibited iocanaseThe slope of a Lineweaver burke plot of the inhibited versus uninhibited iocanase would remain unchanged

Enzymes are protein molecules that increase the rate of reaction by decreasing the activation…

Answered: While furthering your studies of iocane…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

See similar textbooks

Related questions

Question

While furthering your studies of iocane powder you determine that a ceular enzyme, iocase will degrade it. Under normal conditions, iocase shows km 0f 1.85 uM and a kcat of 76. The drug sildenafil was found to have no effect on the km of iocanse yet the kcat was found to drop 58 minutes^-1, when the drug was added and no other changes were made in the reaction conditions. What can be inferred from this data? (remember kcat = vmax/et)

Sildenafil acts as an uncompetitive inhibitor of iocanse
Sildenafil acts as a noncompetitive inhibitor of iocanse
The effect of sildenafil could be countered by adding more iocane to the reaction
The y-intercept of the sildenafil inhibited iocanse would appear to be lower on a Lineweaver burke plot as compared to uninhibited iocanase
The slope of a Lineweaver burke plot of the inhibited versus uninhibited iocanase would remain unchanged

Expert Solution