Which of the following is incorrect about the ATP synthase? O a. The Fo and F₁ components are connected through the gamma subunit O b. None; all the other choices are correct Oc. The c ring rotates as H* are translocated to the matrix Od. Rotation of the c ring causes the gamma subunit to rotate
Q: How many amino acids are in the following peptide? H₂N H3C ZI CH3 IZ O=C CH3 `N H HH OH | LOH
A: A polypeptide chain constitutes of amino acids are linked together via peptide bonds. The proteins…
Q: Complete the interrelated pathways by providing the neccesary metabolite, enzyme, reaction or…
A: Glycolysis is a metabolic pathway during which glucose molecule splits into pyruvate molecules with…
Q: write the detail explation of mode of action of vincristine in detail . write the detail explation…
A: The mitotic cell cycle is constituted of the G1 phase, S phase,G2 phase and M phase. The microtubule…
Q: Which of the following is incorrect about enzyme cofactors? a. Some can be metal ions Ob. None; all…
A: Enzymes are mainly proteins catalyzing a reaction converting susbtrate into product. In addition to…
Q: Answer and draw what is given in the question NEATLY
A: The thermophilic bacteria live at high temperatures like hot springs and hot vents. The Arctic Ocean…
Q: Separation of Amino Acids by Thin Layer Chromatography Lab Questions 1. Describe in detail Thin…
A: Chromatography is a technique used to separate mixtures of substances into individual components. It…
Q: Please answer asap and type your answer and do not copy from anywhere please
A: Glucose is a carbohydrate. Carbohydrates are the hydrates of carbon. Carbohydrates act as the…
Q: 1.Growth factor binding and dimerization Tyrosine kinase domain Growth factor 2. Autophosphorylation…
A: In contrast to G protein-coupled receptors where the cytosolic domain of the receptor is close to…
Q: Which technique is used to characterize multiprotein complexes ?
A: Multiprotein complexes are termed as MPCs that are important for cell signalling. Characterisation…
Q: Given a tripeptide Cys-His-Lys, Cys: Pk1 = 1.71; Pk2 = 10.78; PkR = 8.33 His: Pk1 = 1.82; Pk2 =…
A: pK refers to pH at which a particular group is exactly 50% ionized. A tripeptide is a peptide…
Q: Describe the specific situations where the plasma membrane of cells will not spontaneously re-seal.…
A: The plasma membrane of an eukaryotic cell is a lipid bilayer. The plasma membrane is responsible…
Q: make your own timeline on biochemistry development up to 2022
A: Biochemistry is the study of biochemical reactions and biological process by applying the knowledge…
Q: 1. Proteoglycans, such as heparan sulfate are defined as having sulfated glycosaminoglycans that are…
A: fggd
Q: What if all the data above was the same EXCEPT with the change of G & X? Their new data is below.…
A: The DNA double helix is made of two linked strands that are wound in a helical shape. The two…
Q: Which of the following is incorrect about the chymotrypsin mechanism? a. The (-) charge of oxygen in…
A: The proteolytic activity on the food that enters the intestine is carried out by the protease…
Q: When the amino acid sequence of Hb and Mb is compared, some of them are found to be the same…
A: Hemoglobin and myoglobin are oxygen binding proteins. Hemoglobin helps to carry oxygen from lungs to…
Q: The sequences of four DNA molecules are given bel ii. TTTCCCGGGAAA AAAGGGCCCTTT iv. GCCGGATCCGGC…
A: DNA molecules are the nucleic acids that contain sugar, phosphate and nitrogenous base. Sugar is…
Q: present the chemical mechanism of the HIV protease. Discuss the mode of action of some inhibitors of…
A: - Proteases are enzymes that can break down proteins into peptides. HIV-1 protease (PR) is an…
Q: describe the various stages that are involved in plant regenerative techniques associated with the…
A: Plant regeneration is the technique by which plant cells, tissues, organs etc. can be cultured…
Q: In oxidative phosphorylation, how many molecules of ATP are produced per molecule of NADH in the…
A: The electron transport chain and chemiosmosis are two parts of oxidative phosphorylation that are…
Q: This is a plot under standard conditions of free energy corresponding to a chemical reaction of A+B…
A: The free energy of a reaction is the amount of energy that is actually available to do work. It also…
Q: Which of the following are examples of diffusion (either passive or facilitated)? Glucose in the…
A: The process of diffusion is a passive, spontaneous process and occurs down the concentration…
Q: Calculate the energy produced (in ATP molecules) achieved by complete oxidation of the hydrolysis…
A: Glycolysis is an oxidative process that is common in both aerobic and anaerobic cellular…
Q: Differentiate the levels of protein structure from primary to quaternary.
A: Proteins are biomolecules composed of amino acids. The amino acids are joined together through…
Q: show complete computations/solution
A: Metabolism includes biosynthesis/ reduction (an anabolic process) and oxidation (catabolic…
Q: A) Can you please tell me which of these A.A have a negative side chain? Names of choices in picture…
A: Amino acids are biomolecules that have an amino group, a hydrogen atom, an R group and a carboxyl…
Q: ATP Accounting Upon digestion of strach, isomaltose, one of its degradation products is further…
A: Carbohydrates are principle fuel in the body. Most of the energy is derived from the digestion of…
Q: Answer for the number 11 question. Thank you. No need for long explanation.
A: Glucose is an aldohexose that is utilized as the major source of energy by the body. Glucose is…
Q: 2 When an oxygen molecule binds to the deoxyhemoglobin, multiple conformational changes happen that…
A: Hemoglobin is a protein that carries oxygen from lungs to tissues, and CO2 from tissues to lungs.…
Q: How much index [18] embalming fluid would you need to mix with 15oz of an index [10] embalming fluid…
A: Embalming fluids are a mixture of formaldehyde, glutaraldehyde, methanol and other solvents. It is…
Q: Sickle cell anaemia is caused by a mutation in the HBB gene. The normal wild-type βA allele contains…
A: Sickle cell anemia is a result of a mutation in the HBB gene. This gene contains the restriction…
Q: A biochemist wants to determine the effect of inhibitor A to enzyme B which catlyzes the conversion…
A: Parameters such as Km and Vmax are used for comparing enzyme activities. If we know the initial rate…
Q: Which of the following is incorrect about the peptide Arg-Asp-Cys-Tyr-Gln-Arg-Glu? a. It has six…
A: Basic concept: pI<pH = negatively charged carboxyl group. pI>pH = positively charged amino…
Q: ... A(n) binds to a receptor and elicits a biological effect; while a(n) binds to a receptor but…
A: Binding of certain molecules at their receptors involves the eliciting of response that can be…
Q: Which of the following is incorrect? O a. Metabolic pathways involve mostly intermediates or…
A: Metabolic pathways are very important for a cell to provide energy.metabolic pathways might be…
Q: discuss the significance of the different aseptic techniques utilized in maintaining sterility of…
A: The laboratory that carries out growth of prokaryotic cells or eukaryotic cells in physiological…
Q: Which of the following is incorrect about the rate of an enzyme-catalyzed reaction? O a. It does not…
A: The rate of an enzyme-catalyzed reaction depends on certain factors and one of them is concentration…
Q: Which of the following is incorrect about the enzyme chymotrypsin? Oa. It catalyzes the addition of…
A: Chymotrypsin is a digestive enzyme component of pancreatic juice. The enzyme catalyzes the cleavage…
Q: (a) (c) 1/v + inhibitor 1/[S] (b) + inhibitor X 1/v 1/[S] + inhibitor + inhibitor (d) 1/v 1/V I i…
A: Non competitive inhibition is a type of inhibition where the inhibitor binds to a site other than…
Q: Which of the following is incorrect about chymotrypsin? a. It uses acid-base catalysis Ob. It has…
A: Chymotrypsin is a protease that cleaves the carbonyl side of certain peptide bonds. The protease…
Q: Which of the following is incorrect? a. Without an enzyme, reaction rate can be increased by…
A: Enzymes are the catalysts of biochemical reactions that increase the rate of reaction. Enzymes have…
Q: The patient was admitted with the hypercholesterolemia and atherosclerosis, which of the folowing…
A: Hypercholesterolemia is a disorder that associates with high cholesterol levels in blood. The…
Q: A heptapeptide that puncture the bacterial cell wall has just been recently isolated from the venom…
A: The given flowchart describes the various chemicals that the heptapeptide has been treated with and…
Q: Consider the following DNA strand with the following nucleotide sequence: 3’-ATATCAGAGAATATCA-5’…
A:
Q: In gluconeogenesis, what are the precursors of glucose? Select all that apply. lactate amino…
A: Gluconeogenesis is a process in which glucose is synthesized from non-carbohydrate precursors. This…
Q: What are the possible interferences or complications in detecting and differentiating aldehydes and…
A: Before scientists developed tools such as x-ray crystallography and other spectrophotometric…
Q: i need the answer quickly
A: Given, Heparin used as anticoagulant by binding to antithrombin obstruct clot formation. When…
Q: In another study, inhibitory effects of glucose on the activity of a completely different enzyme,…
A: Enzyme Kinetics - it is a study of the rate of enzyme catalyzed reactions, which can be inhibited by…
Q: Suppose a gene has the sequence ATGGGTTATCGCGAGTAC. A point mutation changes the gene to read…
A: Gene is a segment of DNA that codes for a protein. It transcribes to mRNA which then translates to…
Q: What type of weak interactions stabilize DNA a) salt bridges between bases on opposite strands b)…
A: DNA are polymers of nucleotides. A nucleotide consists of a nitrogenous base(A, T, G, C) attached to…
Step by step
Solved in 2 steps with 1 images
- The first step of the lysozyme reaction (catalytic mechanism) is shown in the figure below. Which statement regarding lysozyme is true? Glu 35 HO O(NAM) R (NAG) Asp 52 a. The local environment of Asp 52 significantly changes its pka. b. Glu 35 has an unusually low pKa due to its hydrophobic environment. c. Glu 35 provides acid/base assistance during catalysis. d. Glu 35 acts as a nucleophile during catalysis.A point mutation in Hb diminishes hydrophobicity at the heme. Which of the following impacts would you predict? . Increased oxidation of Fe2+ and loss of O2 binding b. Decreased negative charges needed at the dimer/dimer interface to stabilize the T-state c. Decreased positive charges needed at the dimer/dimer interface to stabilize the T-state d. Shift the O2 binding curve of Hb to the left e. Decreased affinity for BPG in the T-stateWhat do you think would be the effect on oxidative phosphorylation of the following mutations of F1 or F0 ATPase subunits? Be as specific as possible. A. Subunit c Asp61 to Leu B. Subunit c Asp61 to Asn C. Subunit a Asn214 to Asp D. Subunit a Ser206 to Ala
- Which of the following statements is true? a. Plotting the rate of facilitated transport against substrates gives a sigmoidal curve b. Facilitated carrier proteins can be saturated by substrates c. Both A and B d. Neither A nor B The catalytic triad of chymotrypsin and other serine proteases consists of _________ A. three subunits of the enzyme. B. three amino acid residues close enough in space to make serine a strong nucleophile. C. three enzymes with very similar structural features. D. three amino acid residues adjacent in the primary structure which act to make serine a strong nucleophile. E. None of the above.V-class proton pumps run backward relative to the F-class ATP synthase. Consider the cartoon, which shows the conformations of the beta-subunits and ATPIADP + Pj of the F-class synthase. Which of the following associations between the conformation of the beta subunit and ATP/ADP + P¡ is correct for V- Binding Change Mechanism loose binding ADP+P ATP ATP class pumps? C repeat ADP + P, ADP АТР tight binding АТР +P оpen АТР O The open conformation releases ATP. Hydrolysis of ATP to ADP + P¡ drives the change from tight to loose. O Binding of ADP + P¡ drives change from open to loose. Hydrolysis of ATP to ADP + Pj drives the change from open to loose.All are single-electron carriers EXCEPT: a. UQH2. b. Cyt bL. c. Cyt bH. d. Rieske protein Fe-S clusters. e. Cyt c1. 2.The energy input for the synthesis of glycogen occurs during which of the following enzyme catalysed steps? a. phosphoglucomutase b. UDP-glucose pyrophTosphorylase c. glycogen synthase d. amylo-(1,4®1,6)-transglycosylase e. none of the above require energy input ______________________________________________________________________________(
- 4. The figure below shows ATP in the binding site of pyruvate kinase, an important enzyme in cellular respiration. Note that only amino acids involved in interactions in the binding site are shown. Lys His ATP NH ; afafafor OH OH qat Glu Tyr Asp a. What is the most likely chemical interaction occurring between the tyrosine and the ribose of ATP? b. List one mutation to the lysine (Lys) in the binding site that would likely result in the kinase NOT being able to bind ATP (state the change in amino acid, not in the DNA or mRNA). In one sentence, explain why this mutation would likely lead to this change. Be as specific as possible.ATP Synthase contains with in it one of the most conserved residues in a protein we know. Asp 61. This is the amino acid that carries the proton. a. Why would this residue be so highly conserved? What would happen if a mutation occurred that would change Asp to Ala? b. At the end of one spin of ATP synthase when the proton is in a position to leave to the intermembrane space the Asp comes into close contact with another very highly conserved residue Arg 210. Explain how this Arg residue could help the proton attached to Asp to leave. Hint think pKa Answer both parts with good explanationYou receive kinetic data for a transferase reaction where AX and B are substrates, while A and BX are products. You are asked to establish the reaction mechanism. Which graph will you draw first? A,B,C or D A. 1/Vo against [AXo] at different concentrations of [BXo] B. 1/[AXo] against 1/[Bo] at different concentrations of [BXo] C. 1/Vo against 1/[AXo] at different concentrations of [Bo] / D. 1/Vo against 1/[AXo] at different concentrations of [1/BXo]
- The table contains data about how different ASFV mutants affect enzyme activity-- for example the D29A mutant, where the D at position 29 was mutated to an A. Select three mutants at random, and for each mutant explain how that mutation could affect intermolecular force interactions (an example: hydrogen bonding could be disrupted by this mutation because…Which of the two set ups shall generate higher amount of energy in terms of net ATP generated? Set up A. The one containing 1 mole of trimyristin being catabolized and completely oxidized. Set up B. The one containing combined fatty acids (1mole each) that comprise trymiristin.During cellular respiration, approximately 34 ATP are produced from one molecule of glucose. a. How Many ATP are made during glycolysis? b. How many ATP/GTP are made during the Citric Acid Cycle? c. How many are made during oxidative phosphorylation? d. If you recall electrons from FADH2 pump less proton than electrons from NADH, This is because Complex II does not pump electrons. Because of this FADH2 leads to the production of less ATP, 1 FADH2 produces about 1.5 ATPs Given this value how many ATP are NADH electrons worth? Please answer all parts with good explanation