What is the reaction mechanism to form the 1,4-dihydropyridine A product

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter20: Carboxylic Acids And Nitriles
Section20.SE: Something Extra
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What is the reaction mechanism to form the 1,4-dihydropyridine A product? What is the name of the 1,4-dihydropyridine A?
H3C
OEt
2 eq.
EtO₂C.
H3C
A
CI
CO₂Et CI
CH3
O
CI
CI
EtO₂C.
H3C
B
CO₂Et
CH3
Scheme 1: Reaction of ethyl acetoacetate to form 1,4-dihydropyridine A, which can then be
converted to pyridine B.
Transcribed Image Text:H3C OEt 2 eq. EtO₂C. H3C A CI CO₂Et CI CH3 O CI CI EtO₂C. H3C B CO₂Et CH3 Scheme 1: Reaction of ethyl acetoacetate to form 1,4-dihydropyridine A, which can then be converted to pyridine B.
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