What is the purpose of the Cori cycle?
What is the purpose of the Cori cycle?
In the anaerobic condition of glycolysis, the glucose was hydrolyzed into lactate in the muscle where it enters into the blood and transferred to the liver where gluconeogenesis has taken place. The transfer of glucose that takes place within the liver and muscle is called the Cori cycle.
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The main role of the Cori Cycle is used to regulate lactate which is produced by anaerobic glycolysis metabolism.
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In muscle, the glucose is converted into pyruvate through anaerobic glycolysis which results in the production of energy as ATP.
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lactate dehydrogenase enzyme converted Pyruvate into lactate in the muscle from where the lactate is transported into the bloodstream. if the lactate was left result in accumulation leads to lactic acidosis.
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The liver consists of enzymes for gluconeogenesis which converted the accumulated lactate into glucose gluconeogenesis. further, the glucose was absorbed by the tissues of the cells which result in the production of energy sources in the form of ATP.
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