What are the necessary reagents for the below transformations to occur? Provide a mechanism for b) (the amount of arrows do not indicate the specific number of steps required) a) b) OH oin H CO,CH, ~=~ CO₂CH3 O OH

What are the necessary reagents for the below transformations to occur? Provide a mechanism for b) (the amount of arrows do not indicate the specific number of steps required) a) b) OH oin H CO,CH, ~=~ CO₂CH3 O OH

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter22: Carbonyl Alpha-substitution Reactions

Section22.SE: Something Extra

Problem 26MP: Nonconjugated , -unsaturated ketones, such as 3-cyclohexenone, are in an acid-catalyzed equilibrium...

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Concept explainers

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.

Question

What are the necessary reagents for the below transformations to occur?
Provide a mechanism for b)
(the amount of arrows do not indicate the specific number of steps required)
a)
b)
OH
111
CO,CH,
CO₂CH3
om
H
M
SO
OH

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