Using the pedigree, assume th

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter6: Safe Dosage Calculations
Section: Chapter Questions
Problem A.9CRQ
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Using the pedigree, assume that the disease is caused by an autosomal dominant allele, R. Give the genotype of the following individuals:

(a) III-4 (the girl at lower right)

(b) II-3 (the girl’s mother)

(c) II-4 (the girl’s father)

I
II
2
4
III
1
2 3
4
3.
Transcribed Image Text:I II 2 4 III 1 2 3 4 3.
Expert Solution
Step 1

The pedigree chart is a diagram, which displays the appearance of the phenotypes of a particular gene or organism, and its past generations. It is mainly able to detect diseases that occur over generations. To judge whether the disease is dominant or recessive, one has to check whether the disease occurs in every generation or not. It can be transmitted due to sex-linked transfer, or can be autosomal.

 

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