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- Check the box under each molecule for which the statement in the first column is true. statement It transfers instructions for making a new protein from the nucleus to ribosomes out in the cytoplasm. When attached to a ribosome, each codon specifies the next amino acid in a protein under construction. It usually contains several thousand adenine, uracil, cytosine, and guanine residues. It's secreted by the adrenal cortex, but transported throughout the body to do its job. When combined with a number of different proteins, it forms a large complex in the cytoplasm responsible for synthesizing new proteins. transfer messenger ribosomal RNA RNA RNA 0 [] n UUbiquitin binds to newly synthesized proteins at the ribosome to assist in the protein folding process. True Or FalseWhen a globular cytoplasmic protein folds into its proper tertiary structure, which of the following correctly states the class of amino acids that will be in the interior and the reason why this class will be in the interior? Polar amino acids will be in the interior because they line the binding pocket for a hydrophilic ligand Nonpolar amino acids will be in the interior because they line the binding pocket for a hydrophilic ligand Charged amino acids will be in the interior because they would be bound by ions in the aqueous exterior Nonpolar amino acids would be in the interior because they avoid the exterior aqueous environment. Nonpolar amino acids will be in the interior because the protein would bind the membrane bilayer if they were on the exterior
- If the location in which a protein functions is the endomembrane system then the protein is made on a ribosome attached to the outside of the rough endoplasmic reticulum. As the protein is made it is forced through a pore so that it ends up inside the RER. For each enzyme listed or described below state the kind of ribosome on which it's made (cytosolic, RER). If it's made on a RER ribosome, state the final destination of the protein in the endomembrane system. Protein Ribosome type Location in endomembrane system (if applicable) ACE2 receptor (human protein the SARS-CoV-2 spike protein latches on) A histone protein A mature acid hydrolase that will function as an intracellular lipase Cortisol synthesizing enzyme (hint, cortisol is a steroid lipid) TubulinBecause of the difficulty in doing a flip-flop movement, the lipids need a protein translocator or a flippase. True FalseExplain the roles of large and small subunits of ribosomes.
- Describe the events of protein translation that occur on the surface of a ribosome.Indicate in which category, transcription or translation, each of the following functions belongs: RNA poly-merase, ribosomes, nucleotides, tRNA, pre-mRNA, DNA, anticodon, amino acids.Glycophorins are a type of membrane protein found on red blood cells. They allow red blood cells to circulate through the blood vessels without sticking to the walls of the blood vessels or to other cells. Describe how a glycophorin protein would be synthesized by the cell. Include What parts of the cell are involved and what happens at each location. The process of protein synthesis (i.e. transcription, translation, etc).
- Sequence: AAA UGG CAA Translate the sequence into the correct amino acids. Question 2 options: Lys Trp Stop Lys Trp Gln Stop Lys StopDuring protein synthesis, which of the following are involved in the steps that take place in the nucleus and the steps that take place in the cytoplasm? acetyl transferase RNA polymerase FRNA ribosome MRNA TRNA DNA amino acidsTrace the path of a protein synthesized on a ribosome attached to the rough endoplasmic reticulum (rough ER) as the protein travels to the exterior of the cell. Name all the subcellular structures that the protein passes through. In answering this question, assume that the protein is already produced/synthesized (i.e. don't describe translation).