The following figure shows four compounds, 5a-d, which could potentially react with hydroxide ions to give the molecule acetic acid. of CH3 5a OOH OH CI 5b HO, ? 5c 5d Using your knowledge of carbonyl chemistry, pKa and leaving groups, explain which of the compounds 5a-d will successfully react with hydroxide in the fashion shown. Of those that will react successfully, explain which reaction you expect to be the fastest, and which you expect to be the slowest. (e)

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Which compounds from 5a-d will react with hydroxide in the fashion shown. Which reaction will be the fastest and slowest? Explain using knowledge of carbonyl chemistry, pka and leaving groups. 

The following figure shows four compounds, 5a-d, which could potentially react with
hydroxide ions to give the molecule acetic acid.
CH3
CI
5b
5a
OH
HO.
5c
5d
(e)
Using your knowledge of carbonyl chemistry, pKa and leaving groups, explain which
of the compounds 5a-d will successfully react with hydroxide in the fashion shown.
Of those that will react successfully, explain which reaction you expect to be the
fastest, and which you expect to be the slowest.
Transcribed Image Text:The following figure shows four compounds, 5a-d, which could potentially react with hydroxide ions to give the molecule acetic acid. CH3 CI 5b 5a OH HO. 5c 5d (e) Using your knowledge of carbonyl chemistry, pKa and leaving groups, explain which of the compounds 5a-d will successfully react with hydroxide in the fashion shown. Of those that will react successfully, explain which reaction you expect to be the fastest, and which you expect to be the slowest.
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