Substrates are held in place at the active site of an enzyme with: A. Weak, noncovalent, reversible interactions B. Strong, covalent, reversible interactions C. Weak, noncovalent, irreversible interactions D. Weak, covalent, reversible interactions

Substrates are held in place at the active site of an enzyme with: A. Weak, noncovalent, reversible interactions B. Strong, covalent, reversible interactions C. Weak, noncovalent, irreversible interactions D. Weak, covalent, reversible interactions

General, Organic, and Biological Chemistry

7th Edition

ISBN:9781285853918

Author:H. Stephen Stoker

Publisher:H. Stephen Stoker

Chapter21: Enzymes And Vitamins

Section: Chapter Questions

Problem 21.49EP

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Concept explainers

Vitamins and Coenzymes

A class of organic compounds needed in the human body for normal activities is known as vitamins. They are characterized into two parts depending upon their solubility in water. They can act as coenzymes, cofactors, or prosthetic groups for enzymes.

Question

Substrates are held in place at the active site of an enzyme with:
A. Weak, noncovalent, reversible interactions
B. Strong, covalent, reversible interactions
C. Weak, noncovalent, irreversible interactions
D. Weak, covalent, reversible interactions

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Describe the importance of zymogens in the body. Give an example of an enzyme that has a zymogen.
Describe the difference between graphs showing temperature versus reaction rate for an enzyme-catalyzed reaction and an uncatalyzed reaction.
The site on an enzyme molecule that does the catalytic work is called the: a. binding site. b. allosteric site. c. lock. d. active site.
What is the general role of enzymes in the human body?
The human body has an average pH of about 7 and a temperature of about 37C. Use graphs to illustrate enzyme activity in the human body as a function of the following: a. Substrate concentration b. Enzyme concentration c. pH include pH optimum value d. Temperature include temperature optimum value
Most human enzymes function best in the temperature range of: a. 0C10C b. 10C25C c. 25C40C d. 40C55C
Based on the graphical information in Problem 21-41 about enzymes A and B indicate whether the enzyme activity of enzyme B increases or decreases when the following changes in reaction conditions are made. a. pH decreases from 7.6 to 7.2 b. pH increases from 7.2 to 7.4 c. temperature decreases from 37.8C to 37.6C d. temperature increases from 38.2C to 38.4C