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Question 5-6 Protein kinase A (PKA) can regulate activity of several proteins. Two mutations A and B were identified in the regulatory (R) subunits of PKA. Mutation A in the R subunits of PKA prevents the R subunits from binding cyclic AMP (CAMP). Mutation B in the R subunits of PKA prevents dissociation of the R subunits from the catalytic (C) subunits of PKA. The followings are the possibilities for activity of glycogen synthase and glycogen phosphorylase. A. Stronger activation of glycogen phosphorylase B. Stronger activation of glycogen synthase C. Stronger inhibition of glycogen phosphorylase D. Stronger inhibition of glycogen synthase E. No change of glycogen phosphorylase F. No change of glycogen synthase activity 5. As a consequence of Mutation A, which of the following hormone responses is most likely to be decreased? Enhanced CAMP cellular level will lead to the events of cells with mutation A compared to the activity of glycogen phosphorylase and synthase at their normal CAMP cellular level. in the 2) glucagon; A and D b) glucagon; E and F c) insulin; A and D d) insulin; E and F Your answer: 6. As a consequence of Mutation B, which of the following hormone responses is most likely to he decreased? Enhanced CAMP cellular level will lead to the events of in the

Question 5-6 Protein kinase A (PKA) can regulate activity of several proteins. Two mutations A and B were identified in the regulatory (R) subunits of PKA. Mutation A in the R subunits of PKA prevents the R subunits from binding cyclic AMP (CAMP). Mutation B in the R subunits of PKA prevents dissociation of the R subunits from the catalytic (C) subunits of PKA. The followings are the possibilities for activity of glycogen synthase and glycogen phosphorylase. A. Stronger activation of glycogen phosphorylase B. Stronger activation of glycogen synthase C. Stronger inhibition of glycogen phosphorylase D. Stronger inhibition of glycogen synthase E. No change of glycogen phosphorylase F. No change of glycogen synthase activity 5. As a consequence of Mutation A, which of the following hormone responses is most likely to be decreased? Enhanced CAMP cellular level will lead to the events of cells with mutation A compared to the activity of glycogen phosphorylase and synthase at their normal CAMP cellular level. in the 2) glucagon; A and D b) glucagon; E and F c) insulin; A and D d) insulin; E and F Your answer: 6. As a consequence of Mutation B, which of the following hormone responses is most likely to he decreased? Enhanced CAMP cellular level will lead to the events of in the

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Tools Window Help a Practice Final Exam Key Chem 317.pdf (page 3 of 23) 46% O Thu 5:20 PM Q Search Question 5-6 Protein kinase A (PKA) can regulate activity of several proteins. Two mutations A andB were identified in the regulatory (R) subunits of PKA. Mutation A in the R subunits of PKA prevents the R subunits from binding cyclic AMP (CAMP). Mutation B in the R subunits of PKA prevents dissociation of the R subunits from the catalytic (C) subunits of PKA. The followings are the possibilities for activity of glycogen synthase and glycogen phosphorylase. A. Stronger activation of glycogen phosphorylase B. Stronger activation of glycogen synthase C. Stronger inhibition of glycogen phosphorylase D. Stronger inhibition of glycogen synthase E. No change of glycogen phosphorylase F. No change of glycogen synthase activity 5. As a consequence of Mutation A, which of the following hormone responses is most likely to be decreased? Enhanced CAMP cellular level will lead to the events of cells with mutation A compared to the activity of glycogen phosphorylase and synthase at their in the normal cAMP cellular level. glucagon; A and D b) glucagon; E and F c) insulin; A and D d) insulin; E and F Your answer: 6. As a consequence of Mutation B, which of the following hormone responses is most likely to be decreased? Enhanced cAMP cellular level will lead to the events of in the houlone at their
Transcribed Image Text:Tools Window Help a Practice Final Exam Key Chem 317.pdf (page 3 of 23) 46% O Thu 5:20 PM Q Search Question 5-6 Protein kinase A (PKA) can regulate activity of several proteins. Two mutations A andB were identified in the regulatory (R) subunits of PKA. Mutation A in the R subunits of PKA prevents the R subunits from binding cyclic AMP (CAMP). Mutation B in the R subunits of PKA prevents dissociation of the R subunits from the catalytic (C) subunits of PKA. The followings are the possibilities for activity of glycogen synthase and glycogen phosphorylase. A. Stronger activation of glycogen phosphorylase B. Stronger activation of glycogen synthase C. Stronger inhibition of glycogen phosphorylase D. Stronger inhibition of glycogen synthase E. No change of glycogen phosphorylase F. No change of glycogen synthase activity 5. As a consequence of Mutation A, which of the following hormone responses is most likely to be decreased? Enhanced CAMP cellular level will lead to the events of cells with mutation A compared to the activity of glycogen phosphorylase and synthase at their in the normal cAMP cellular level. glucagon; A and D b) glucagon; E and F c) insulin; A and D d) insulin; E and F Your answer: 6. As a consequence of Mutation B, which of the following hormone responses is most likely to be decreased? Enhanced cAMP cellular level will lead to the events of in the houlone at their
Thu s20 PM Practice Final Evam tay Cham ge s of 2) normal CAMP cellular level. glucagon; A andD bglucagon; E and F c) insulin; A and D d) insulin; E and F Your answer 6. As a consequence of Mutation B, which of the following hormone responses is most likely to be decreased? Enhanced CAMP cellular level will lead to the events of cells with mutation B compared to the activity of glycogen synthase and phosphorylase at their normal CAMP cellular level. a) glucagon; E and F b) glucagon; B and C c) insulin; E and F d) insulin; B and C Your answer in the
Transcribed Image Text:Thu s20 PM Practice Final Evam tay Cham ge s of 2) normal CAMP cellular level. glucagon; A andD bglucagon; E and F c) insulin; A and D d) insulin; E and F Your answer 6. As a consequence of Mutation B, which of the following hormone responses is most likely to be decreased? Enhanced CAMP cellular level will lead to the events of cells with mutation B compared to the activity of glycogen synthase and phosphorylase at their normal CAMP cellular level. a) glucagon; E and F b) glucagon; B and C c) insulin; E and F d) insulin; B and C Your answer in the
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