Provide the product you would get if you first did an ozonolysis reaction. HO Me step 1.03, then Me2S step 2.0 CI product? Me AlCl3

In both examples below the reactants shown are combined to bring about a nucleophilic substitution (Sy1, Sy2) and/or elimination (E1, E2) reaction. What is the major reaction that takes place in each case? CI CH2CI NaOH H20 SN2 E2 mixture of SN1 and E1 CH3 CI CH3OH CH3

For each of the following reactions, predict the major product. H2N HO 1. H2NNH2, acetic acid 2. NaOH, A .CN H20 H2SO4

In both examples below the reactants shown are combined to bring about a nucleophilic substitution (Sn1, Sn2) and/or elimination (E1, E2) reaction. What is the major reaction that takes place in each case? CH2CI NaOH H2O CH3 CH3 CH,CH,CHCCH, H20

Consider each elementary step present in the mechanism of an acid-catalyzed hydrolysis of a nitrile. Draw the organic intermediate after each elementary step. NOTE from Dr. Mahoney: Your mechanism will only cover the hydrolysis of a nitrile to an amide product. It will not cover the conversion of the amide to the final carboxylic acid H30* H₂O Step 3 Step 5 Step 4 11 N

Choose the best reagents to complete the reaction shown below. HO 0= 0= OH e A B C D E 1.03 2. HOẠC mCPBA 2. H3O+ 1. Hg(OAc)2, H₂O 2. NaBH4, NaOH RCO3H 1. OsO4 (catalytic),

3B Complete the reactions below. OH NaBr/H₂SO4 D Mg Et₂O E (2 ισοδ) 1. HCOOEt Et₂O 2. H₂O/H* F

Give the major product of the following reaction. NO, NaOH H+ O,N- heat NO, O,N NO2 O,N- OMe -N F- N- H There is no reaction under these conditions or the correct answer is not listed here. O,N OMe Meo F OMe NO2 O,N- H. O,N F H.

Draw the major product of this reaction. Ignore inorganic byproducts, methanal (H₂CO) or CO2. 1 11 L 1 11 1. OSO4, H2O 2. NalO4 3. Na2S2O3, H2O I LE U Drawing 1

2 a) Listen Select the expected product of the following reaction sequence. 1. NaH 1. O3 1. LIAIH4, THF 4 2. H20 2. Br 2. Zn, HCI OH