Provide a detailed mechanism for the following reactions and determine the major product: a) b) НО. H + + O HN. LOCH 3 H H₂SO4 MeOH NaBH3CN, ACOH pH = 4 NaOH, EtOH A

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter22: Carbonyl Alpha-substitution Reactions
Section22.SE: Something Extra
Problem 64AP: The key step in a reported laboratory synthesis of sativene, a hydrocarbon isolated from the mold...
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Provide a detailed mechanism for the following reactions and determine the major
product:
a)
b)
O
НО.
H +
HN.
LOCH3 H₂SO4
MeOH
the
+ H
NaBH3CN, ACOH
pH = 4
NaOH, EtOH
A
Transcribed Image Text:Provide a detailed mechanism for the following reactions and determine the major product: a) b) O НО. H + HN. LOCH3 H₂SO4 MeOH the + H NaBH3CN, ACOH pH = 4 NaOH, EtOH A
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