Problem 2. Lactic acidosis (abnormally high concentration of lactic acid in blood) occurs because of shock. 1. Explain how low oxygen levels promote lactate production. 2. Explain how maintaining low energy charge measured by the [NADH]/[NAD'] is crucial for continued production of lactate. 3. Explain how low [NADH]/[NAD'] is maintained while oxygen levels remain low.

Cardiopulmonary Anatomy & Physiology
7th Edition
ISBN:9781337794909
Author:Des Jardins, Terry.
Publisher:Des Jardins, Terry.
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Problem 2. Lactic acidosis (abnormally high concentration of
lactic acid in blood) occurs because of shock.
1. Explain how low oxygen levels promote lactate production.
2. Explain how maintaining low energy charge measured by
the [NADH]/[NAD'] is crucial for continued production of
lactate.
3. Explain how low [NADH]/[NAD'] is maintained while
oxygen levels remain low.
Transcribed Image Text:Problem 2. Lactic acidosis (abnormally high concentration of lactic acid in blood) occurs because of shock. 1. Explain how low oxygen levels promote lactate production. 2. Explain how maintaining low energy charge measured by the [NADH]/[NAD'] is crucial for continued production of lactate. 3. Explain how low [NADH]/[NAD'] is maintained while oxygen levels remain low.
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