Answered: Predict the major products of the…

Predict the major products of the following base-catalyzed aldol condensations withdehydration.(a) benzophenone (PhCOPh) + propionaldehyde(b) 2,2@dimethylpropanal + acetophenone

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter19: Enolate Anions And Enamines

Section: Chapter Questions

Problem 19.82P: The following molecule undergoes an intramolecular reaction in the presence of pyrrolidinium...

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Concept explainers

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.

Question

Predict the major products of the following base-catalyzed aldol condensations with
dehydration.
(a) benzophenone (PhCOPh) + propionaldehyde
(b) 2,2@dimethylpropanal + acetophenone

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