Porcine dynorphin is a neuropeptide having 17 amino acid residues. Its structure is shown below. Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln How does trypsin catalyze the hydrolysis of peptides? You can answer this question by identifying the amino acids involved and whether the hydrolysis is at their amino side or the carboxyl side or if particular amino acids end up at the N-teminal end or at the C-terminal end.
Q: Can you please help find what Glutamate is?
A: Amino acids are the smallest entities that make up the proteins or peptides via peptide bond…
Q: Draw Glu-His-Trp-Ser-Gly-Leu-Arg-Pro-Gly peptide. What is the net charge of this peptide at pH 3, 8…
A: polypeptides are made up of amino acids that are joined together by peptide bonds (covalent in…
Q: (b) r , The following polypeptide sequence has three alpha helices and two B turns. Based on what we…
A: An amino group and an acid group-containing organic molecules are called Amino acids.…
Q: What is the difference between the structures of the following two peptides: Name them.…
A: There are 20 standard amino acids that make up all the proteins inside the cell. The amino acids are…
Q: Determine the net charge of the peptide below at pH 7 and 12. Show your solution.…
A: Given peptide sequence: Thr-Glu-Pro-Ile-Val-Ala-Pro-Met-Glu-Tyr-Gly-Lys At low pH, a peptide is…
Q: Indicate all the possible sequences for a tripeptide containing alanine, glutamine, and methionine;…
A: A peptide is the sequence of amino acids that are joined through the formation of peptide bond in…
Q: The sequence of a 29 aa long peptide can be determined from the following data. a) Treatment of the…
A: Amino acids are the molecules that join to form a protein structure. The bond formed between two…
Q: Write the structure of each of the following peptides. Start with the N-terminal and the COO- on the…
A: Peptides are the sequence of amino acids that are joined through formation of peptide bond. The…
Q: Is this the correct answer of finding what the charge is?
A: Amino acids are the smallest units that make up the peptides or proteins inside the cell. Twenty…
Q: Hydrolysis of dodecapeptide P with the enzyme trypsin affords the following fragments: Glu-Ala-Lys,…
A: Trypsin cleaves the dodecapeptide at the carboxyl side of Lys or Arg. Chymotrypsin cleaves the…
Q: Why is B-D-Glucopyranose in a chair conformation form is the most stable form of glucose present in…
A: B-D-Glucopyranose is a form of D-glucose which is a hexose monosaccharide unit that consists of six…
Q: Write the name of the oligopeptide L-E-T-S-P-R-A-Y using their full amino acid names. Draw the…
A: Amino acids are molecules that serve as monomers for proteins. Each amino acid is composed of a…
Q: In some proteins, the side chain of serine appears to undergo ionization. Explain why ionization…
A: Serine proteases like chymotrypsin are most studied biological enzyme and uses covalent modification…
Q: Write the following oligopeptide using the one letter code for the amino acids: Cys-His-lle-Leu-Glu…
A: One letter code has been assigned to each and every amino acids and is often used to represent the…
Q: The oligopeptide isolated from the brain of an animal has the sequence…
A: Introduction :- Proteins are made up amino acids ( linked with each other by the help of peptide…
Q: Give the amino acid sequence of an octapeptide that contains the amino acids Tyr, Ala, Leu (2…
A: Introduction: There are 20 known amino acids at present. These are biomolecules that form proteins…
Q: The endorphins are a group of naturally occurring neurotransmitters that act in a manner like…
A:
Q: What amino acid/s is/are isolated when Ala-Lys-Val-Phe—His-Tyr-Gly is treated with trypsin and…
A: Trypsin and chymotrypsin are serine proteases. Both these proteases catalyze the hydrolysis of…
Q: Porcine dynorphin is a neuropeptide having 17 amino acid residues. Its structure is shown below.…
A: Since you have posted a question with multiple sub-parts, we will solve first three sub- parts for…
Q: Pyrrolysine (Pyl, O) and Selenocysteine (Sec, U) are two uncommon amino acids. Knowing that these…
A: Amino acids are monomers that make up proteins. 20 different amino acids are commonly found in…
Q: Imagine the main chain of a protein bends back on itself, so that two amino acid residues R, and R,…
A: Protein folding is the physical process by which a polypeptide chain is folded into its…
Q: Given the polypeptide chain below: Ala-Arg-Val-His-Asp-Gln Which amino acid/s is/are hydrophobic?…
A: The organic molecule is comprised of two functional groups that are an amino group and the carboxyl…
Q: Treatment of a polypeptide with 2-mercaptoethanol yields two polypeptides 1.…
A: Given that treatment of a polypeptide with 2 marcaptoethanol yielded 2 polypeptides: 1.…
Q: Consider a mutation that results in a substitution of Cysteine (CYS) ) for Tyrosine (TYR) at…
A: Cysteine is a polar amino acid. Cysteine is a triprotic acid with three ionizable functional…
Q: V-M-Y-F-E-N: This is the single-letter amino acid abbreviation for a peptide. What is the net charge…
A: Amino acids are biomolecules that join together by an amide bond to form a peptide molecule. The…
Q: Consider a hexapeptide of the sequence thr asn glu trp lys gln. After complete hydrolysis, which…
A: Asked : Amino acid which elutes first
Q: How many peptide bonds in this peptide chain LEU-ILE-LEU?
A: A peptide bond is an amide kind of covalent chemical connection that connects two successive…
Q: Consider the following peptide. Gly-Lys-Ala-Val-Asp-Gly-lle-Val-Lys-Ala-Gly-His-Glu-Ala a) What…
A: Since multiple questions are posted, only the first two are answered in this section, if you require…
Q: Name the peptide * он H,'N-CH-C-N-CH-C-N-CH-C-O CH, CH-CH, CH, H он H. CH, CH, CH, SH CH,…
A: Peptides are composed of amino acids linked to each other via a peptide bond. Peptides are named…
Q: The following peptide (alanylglutamylglycylalanylleuci ne) has.. O A disulfide bridge. O Five…
A: Different amino acids are connected via the peptide bond to form a peptide. Each amino acid has a…
Q: Two melanocyte-stimulating hormones have the following amino acid sequences. Take a highlighter or…
A: Conserved sequences are the amino acid sequence that remain identical between two or more species…
Q: A heptapeptide was analyzed by Pinky. She reacted it with carboxypeptidase and found out that it…
A: Protein sequencing is the method used for determining the amino acid sequence or the primary…
Q: What is the net charge at pH 7 on a peptide with the following sequence?…
A: Amino acids are the building blocks of proteins which are composed of amino group (NH3+), carboxyl…
Q: Consider the peptide Asp-Lys-Phe-Glu-Asn-Tyr-Gln-Val-Cys. In a single beaker, you treat this peptide…
A: The amino acids that form peptide chains can be either polar/non-polar, charged/uncharged,…
Q: Explain why the indole nitrogen of tryptophan is more weakly basic than one of the imidazole…
A: "Since there is multiple question present, I have answered the first question for you. If you need a…
Q: Draw a peptide from the given amino acids Phe-Cys-Ala-Arg-Ala-Ser-Tyr. Try to cleave this…
A: Pepsin has a broad cleavage specificity but has a greater propensity to cleave near hydrophobic…
Q: The melanocyte-stimulating peptide hormone a-melanotropin has the following sequence:…
A: Melanocyte-stimulating hormone, α-melanotropin is an endogenous peptide hormone and neuropeptide of…
Q: You have isolated the following peptide: His-Ser-Arg-Ala-Glu-Leu-Pro-Gly A) Calculate the…
A: The given peptide is composed of histidine, serine, arginine, alanine, glutamate, leucine, proline…
Q: The melanocyte-stimulating hormone a-melanotropin has the following sequence:…
A: Aminoacids are the building blocks of proteins that are linked by peptide bond. The sequence of…
Q: A peptide has the following sequence: Gly-Ala-Lys-Phe-Asp-Met-Val-Pro-Arg-Ala-Leu. What is the net…
A: The amino acids contain ionizable groups. The ionic form and charge of the amino acids depend upon…
Q: The primary structure of b-endorphin, a peptide containing 31 amino acids synthesized by the body to…
A: Trypsin is a serine protease that is present in the digestive system of vertebrates. It is an…
Q: What is the net electric charge of a peptide that has the sequence and provide the one letter code…
A: The amino acids are composed of an amino group, a carboxyl group, a hydrogen atom, and a variable…
Q: Trypsin cleaves a polypeptide backbone at the C-terminal side of Arg or Lys residues, whereas…
A: Polypeptide is formed when amino acids are joined together with peptide bonds. Peptide bond is…
Q: A peptide has the sequence Glu-His–Trp–Ser-Gly-Leu-Arg-Pro-Gly The pK, values for the peptide's side…
A: Amino acids have alpha amino and carboxyl groups that can be titrated. Some amino acids have side…
Q: Can you please describe the specific components that each of these structures are comprised of (…
A: Proteins are the biomolecules which are made up of amino acids. Amino acids are joined together with…
Q: The bacterially produced antibiotic gramicidin A forms channels in cell membranes that allow the…
A: Antibiotics are molecules/compounds that have bacteriostatic or bactericidal effects. They are…
Q: Using the following data, determine the correct sequence of the octapeptide. Edmund's Reaction =…
A: Chains of Amino acids are held together through a peptide bond to form a structure known as…
Trending now
This is a popular solution!
Step by step
Solved in 3 steps
- If phenylalanine was not an essential amino acid, would diet therapy (the elimination of phenylalanine from the diet) for PKU work?Porcine dynorphin is a neuropeptide having 17 amino acid residues. Its structure is shown below. Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln How does trypsin catalyze the hydrolysis of peptides? You can answer this question by identifying the amino acids involved and whether the hydrolysis is at their amino side or the carboxyl side or if particular amino acids end up at the N-teminal end or at the C-terminal end. List down the different fragments that would result if dynorphin were cleaved by trypsin. . How does chymotrypsin catalyze the hydrolysis of peptides? You can answer this question by identifying the amino acids involved and whether the hydrolysis is at their amino side or the carboxyl side or if particular amino acids end up at the N-teminal end or at the C- terminal end. List down the different fragments that would result if dynorphin were cleaved by chymotrypsin. . Cyanogen bromide is a chemical reagent which also cleaves peptide bonds. What is/are…The melanocyte-stimulating hormone a-melanotropin has the following sequence: Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val In the one-letter code of amino acids, this sequence would be: SYSMEHFRWGKPV STSMGHFAWGKPV O SYSMDHFAWGKPV O SYSMEHFAWGLPV
- After the polypeptide shown below was treated with maleic anhydride, it was hydrolyzed by trypsin. (After a polypeptide is treated with maleic anhydride, trypsin will cleave the polypeptide only on the C-side of arginine.) Gly-Ala-Asp-Ala-Leu-Pro-Gly-Ile-Leu-Val-Arg-Asp-Val-Gly-Lys-Val-Glu-Val-Phe-Glu-Ala-Gly-Arg-Ala-Glu-Phe-Lys-Glu-Pro-Arg-Leu-Val-Met-Lys-Val-Glu-Gly-Arg-Pro-Val-Gly-Ala-Gly-Leu-Trp In what order will the fragments be eluted from an anion-exchange column using a buffer of pH = 5?H CH₂ H₂C HC-CH3 CH₂ H H₂C (S) H₂C H CH₂ CH₂ CH₂ NH O C NH NH₂ a) Which of the following statements about this peptide are correct? Group of answer choices Treatment of this peptide with trypsin generates two products. This peptide is a substrate for carboxypeptidase A Treatment of this peptide with cyanogen bromide generates a pentapeptide and a tripeptide. Treatment of this peptide with chymotrypsin generates three products. Treatment of this peptide with elastase generates 2 products. None of the above statements are correct. b) What is the sequence of this peptide using one letter abbreviations? c) What is the pH which would correspond to the ionization of the peptide as drawn above? 1, 5, 7, 10, 14Draw a peptide for cys-asn- pro-gly (Using the same format in picture)
- V-M-Y-F-E-N: This is the single-letter amino acid abbreviation for a peptide. What is the net charge of this peptide at pH 7.0? An enzyme called a protein tyrosine kinase can attach phosphates to the hydroxyl groups of tyrosine (Y). What is the net charge of the peptide at pH 7.0 after it has been phosphorylated by a tyrosine kinase? What is the likely source of phosphate used by the kinase for this reaction?An oligopeptide has the following amino acid sequence: NH2-Ala-Glu–Leu–Trp–Tyr-Ser–Gly–Lys–Leu-Ala–Arg-Ala-Phe-Ile-Pro–Gly-COOH a) Estimate the net electric charge of the molecule at pH 8.0 and pH 11.0. b) If the above peptide is passed through a cation exchange chromatographic column (that is, the matrix of the column has negative charges) stabilized at pH 8.0, would you expect it to be retained on the column? c) Indicates the number of fragments, and the sequence of each of them, that would be obtained when treating the peptide in question with: i) trypsin, ii) chymotrypsin.Consider the following peptide: Lys-His-Asp-Glu-Phe-Cys-Ala-Asp-His-Arg What is the net charge of this peptide at pH = 1? What is the net charge of this peptide at pH = 14?
- The melanocyte-stimulating peptide hormone α-melanotropin has the following sequence: Ser–Tyr–Ser–Met–Glu–His–Phe–Arg–Trp–Gly–Lys–Pro–Val(a) Write the sequence using the one-letter abbreviations.(b) Calculate the molecular weight of α-melanotropin, using data in as shown.The melanocyte-stimulating peptide hormone a-melanotropin has the following sequence: Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val (a) Write the sequence using the one-letter abbreviations. (b) Calculate the molecular weight of a-melanotropin, a da'Draw the structure of the peptide: Val-His-Leu-Thr-Pro-Val-Glu-Lys-Ser-Ala-Val-Thr What is the significance of the peptide described?