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What kind of benefits will be gained in the terms of patient approach by pharmacogenomic tests?
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- BiDil® is indicated for the treatment of heart failure as an adjunct to standard therapy in self-identified black patients to improve survival, to prolong time to hospitalization for heart failure, and to improve patient-reported functional status Question: The results of BiDil® clinical trials were compelling…Expound on the results. Question : What role did FDA’s approval resulted in BiDil® being a great example of pharmacogenomics/pharmacogenetics in the U.S.?Explain a simple test one could do to determine if drug resistance isdeveloping in a culture.Why should clinical trials reflect the diversity of the American population?
- Which of the following would NOT be a reason that a clinical trial is unethical? a) Researchers are in a state of equipoise for the two treatments under study b) The sample size is very small c) The benefits to participants are outweighed by the potential risks d) The researchers already know that one treatment is better than the otherDefine the following terms:• Preclinical Trial• Clinical Trials• FDA Review• Lead discovery• Molecular target-based screening• Phenotypic screeningHow are microarrays used to analyse the response of cells in drug therapy
