Part II-A New Dilemma Suzanne and David decided that Suzanne would take the diagnostic test. In preparing for a possible positive result, they increased the value of Suzanne's life insurance and purchased the best long-term care policy available. They also prayed together and promised each other that the test results would not change them, only prepare them for the future. The doctor swabbed the inside of Suzanne's cheek to obtain some cells. The DNA was extracted from these cells and tested for the gene. Suzanne's test came back positive-she had inherited the gene mutation APP from her father. When they got the news, Suzanne reacted with tearful stoicism, David with stunned silence. Suzanne and David now have a new dilemma. They have always wanted to have children, but understand that each of their children now has a 50% chance of inheriting the disease. In addition, it is likely that Suzanne will not be able to raise (or even recognize) her children as her disease progresses. This would have an impact on all of them-Suzanne, David, and any children they might have. Should they have children? Questions 1. What role is played by meiosis, oogenesis, and spermatogenesis in human reproduction? How is it possible that 50% of Suzanne's eggs will be carrying the mutated APP gene? 2. What is DNA? A gene? An allele? How do genes determine traits? 3. The APP gene codes for a particular protein. Why does a mutated APP gene lead to problems in the brain? What are the two other genes (and their resulting gene products-the proteins) that, when mutated, can lead to EOFAD? How does each protein play a role in brain function?
Part II-A New Dilemma Suzanne and David decided that Suzanne would take the diagnostic test. In preparing for a possible positive result, they increased the value of Suzanne's life insurance and purchased the best long-term care policy available. They also prayed together and promised each other that the test results would not change them, only prepare them for the future. The doctor swabbed the inside of Suzanne's cheek to obtain some cells. The DNA was extracted from these cells and tested for the gene. Suzanne's test came back positive-she had inherited the gene mutation APP from her father. When they got the news, Suzanne reacted with tearful stoicism, David with stunned silence. Suzanne and David now have a new dilemma. They have always wanted to have children, but understand that each of their children now has a 50% chance of inheriting the disease. In addition, it is likely that Suzanne will not be able to raise (or even recognize) her children as her disease progresses. This would have an impact on all of them-Suzanne, David, and any children they might have. Should they have children? Questions 1. What role is played by meiosis, oogenesis, and spermatogenesis in human reproduction? How is it possible that 50% of Suzanne's eggs will be carrying the mutated APP gene? 2. What is DNA? A gene? An allele? How do genes determine traits? 3. The APP gene codes for a particular protein. Why does a mutated APP gene lead to problems in the brain? What are the two other genes (and their resulting gene products-the proteins) that, when mutated, can lead to EOFAD? How does each protein play a role in brain function?
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter8: The Structure, Replication, And Chromosomal Organization Of Dna
Section: Chapter Questions
Problem 3CS: Should he go ahead and enroll on the chance that he would receive the DNA vaccine and that it would...
Related questions
Question
Please help me answer questions 1 and 5 in part 2 of this case study,
Thank you
A copy of the PDF link https://www.cusd80.com/cms/lib/AZ01001175/Centricity/Domain/8922/eofad.pdf
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 4 steps
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Recommended textbooks for you
Human Heredity: Principles and Issues (MindTap Co…
Biology
ISBN:
9781305251052
Author:
Michael Cummings
Publisher:
Cengage Learning
Human Heredity: Principles and Issues (MindTap Co…
Biology
ISBN:
9781305251052
Author:
Michael Cummings
Publisher:
Cengage Learning
Principles Of Radiographic Imaging: An Art And A …
Health & Nutrition
ISBN:
9781337711067
Author:
Richard R. Carlton, Arlene M. Adler, Vesna Balac
Publisher:
Cengage Learning