non-cancer risk

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter10: Reconstitution Of Powdered Drugs
Section: Chapter Questions
Problem 42SST
icon
Related questions
Question
A person (70kg) eating locally caught fish from water contaminated with 100ppb TCE and 100ppb aniline. The bioconcentration value for TCE and aniline in fish is the same at 1.06mg TCE (or aniline) per kg fish, respectively. Fish is only exposed to these contaminants in its environment. About 54g of fish is consumed in 350days/yr for 30years. Assume bioavailability value of 1. The potency factor for TCE is 1.1 × 10$# kg.day/mg and reference dose is 1.00 × 10$% mg/kg.day. Whereas the potency factor for aniline is 5.7 × 10$" kg.day/mg and reference dose (based on drinking water) is 1.60 × 10$& ??/L. Unlike aniline, TCE is not a carcinogenic compound. There are 70yrs in a lifetime and 365day/yr. - Using chronic daily intake calculation, determine the non-cancer risk (number of people in one million) for the above case.
Expert Solution
steps

Step by step

Solved in 2 steps with 1 images

Blurred answer
Knowledge Booster
Medical terminologies
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Curren'S Math For Meds: Dosages & Sol
Curren'S Math For Meds: Dosages & Sol
Nursing
ISBN:
9781305143531
Author:
CURREN
Publisher:
Cengage