Mutations in the Galactose-1-Phosphate Uridyl Transferase Gene Can you use RFLP to identify this mutation?
Mutation --It is an alteration in the sequence of nucleotides in a genome of an organism , virus ,viral genome and extrachromosomal DNA .
RLFP -- It is defined as Restriction Fragments Length Polimorphisms analysis can be used as form of genetic testing to observe whether an individual carries a mutant gene for a disease which is running in the family , result from variation in the DNA sequencing recognized by restriction enzymes .,
Typically gel electrophoresis is used to visualize RFLPs .
Principle of RFLP ---One of the earliest molecular markers developed for genetic mapping the base is any genomic DNA can be differentiated according to the presence or absence of restriction enzymes sites .
Use--In fingerprinting forensic uses RFLP analysis to identify suspect .
Paternity RFLP is used to determination for tracing ancestry .
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