In the current experiment, we will use a different electrophile (the tert.-butyl cation) to alkylate 1,4-dimethoxybenzene. This is a Friedel-Crafts Alkylation reaction. LOCH3 (H;C);C. LOCH3 (CH3);COH CH;COOH/H,SO4 H;CO H;COʻ `C(CH3)3

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In the current experiment, we will use a different electrophile (the tert.-butyl cation) to alkylate
1,4-dimethoxybenzene. This is a Friedel-Crafts Alkylation reaction.
LOCH3
(H;C);C,
LOCH3
(CH3);COH
CH;COOH/H,SO4
H;CO
H;CO
`C(CH3)3
Transcribed Image Text:In the current experiment, we will use a different electrophile (the tert.-butyl cation) to alkylate 1,4-dimethoxybenzene. This is a Friedel-Crafts Alkylation reaction. LOCH3 (H;C);C, LOCH3 (CH3);COH CH;COOH/H,SO4 H;CO H;CO `C(CH3)3
The mechanism of the above reaction is:
(CH3);COH
+ H2SO4
(CH3);C-
+
HSO,
LOCH3
-H
(H3C);C
(CH3)3C
OCH3
H3CO
H;CO
H3C)3C.
LOCH3
(H3C);C.
LOCH3
(CH3);C-
H3CO
C(CH3)3
H3CO
Transcribed Image Text:The mechanism of the above reaction is: (CH3);COH + H2SO4 (CH3);C- + HSO, LOCH3 -H (H3C);C (CH3)3C OCH3 H3CO H;CO H3C)3C. LOCH3 (H3C);C. LOCH3 (CH3);C- H3CO C(CH3)3 H3CO
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