In preparing an infusion of the drug cetuximab, a pharmacist adds 15 mL of bacteriostatic water for injection to a vial containing 350 mg of the mAb. The resulting solution contains cetuximab, 24 mg/mL. Loading dose = 4 mg/kg (120 min infusion); maintenance dose = 1.8 mg/kg/wk (60 min infusion) (a) calculate the milliliters of solution required for the loading dose for a 200-lb patient. The pharmacist then transfers the calculated volume into an infusion bag containing 300 mL of sodium chloride injection. Calculate (b) the quantity of cetuximab administered in mg/min and (c) the drip rate, in drops/minute, using an administration set that delivers 15 drops/mL. O a, 21 mL; 3.62 mg/min; 30 drops/min O b.21 mL; 4.56 mg/min; 30 drops/min O. 15.16 mL; 3.03 mg/min; 23 drops/min Od. 15.16 mL; 3.03 mg/min; 39.39 drops/min
In preparing an infusion of the drug cetuximab, a pharmacist adds 15 mL of bacteriostatic water for injection to a vial containing 350 mg of the mAb. The resulting solution contains cetuximab, 24 mg/mL. Loading dose = 4 mg/kg (120 min infusion); maintenance dose = 1.8 mg/kg/wk (60 min infusion) (a) calculate the milliliters of solution required for the loading dose for a 200-lb patient. The pharmacist then transfers the calculated volume into an infusion bag containing 300 mL of sodium chloride injection. Calculate (b) the quantity of cetuximab administered in mg/min and (c) the drip rate, in drops/minute, using an administration set that delivers 15 drops/mL. O a, 21 mL; 3.62 mg/min; 30 drops/min O b.21 mL; 4.56 mg/min; 30 drops/min O. 15.16 mL; 3.03 mg/min; 23 drops/min Od. 15.16 mL; 3.03 mg/min; 39.39 drops/min
Chapter11: Properties Of Solutions
Section: Chapter Questions
Problem 109AE: Patients undergoing an upper gastrointestinal tract laboratory test are typically given an X-ray...
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