Answered: In individuals affected by cystic…

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...

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Question

In individuals affected by cystic fibrosis, salt crystals may appear after
perspiration dries up. In addition, the disease causes respiratory disorders
which can be both debilitating and lethal. It occurs in individuals homozygous
for the recessive gene. Two normal parents had a daughter with the
symptoms of this disease, and a normal son who marries a normal woman
with an afflicted A test (salt concentration in perspiration of heterozygotes is
higher than normal) disclosed that both are indeed carriers of the gene. If the
first child born to the mating in (b) was defective, what is the probability that
the 2nd child would also be defective?
Express answer in fraction form

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