If the blood glucose test was performed on people from the Maasai population in Kenya, would their results be lactase persistent or nonpersistent. Explain your prediction. The Maasai raise cows for food.
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If the blood glucose test was performed on people from the Maasai population in Kenya, would their results be lactase persistent or nonpersistent. Explain your prediction. The Maasai raise cows for food.
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- On the right is a diagram of plasma concentration of three metabolites: glucose, B- hydroxybutyrate, and free fatty acid of an experimental animal over weeks of starvation. 4. (a) Label the lines with the names of the three metabolites. Yellow: Red: 10 20 30 40 Blue: Days of starvation (b) What factor in the plasma binds to and transports free fatty acid (c) Where was B-hydroxybutyrate produced? Why it is produced? What are the purposes of producing it (d) How B-hydroxybutyrate is used as fuel in extrahepatic cells? Write down the reactions, enzymes, and cofactors (No need to elaborate on the TCA cycle). (e) How many ATP molecules or equivalent are generated after complete oxidation of one molecule of B-hydroxybutyrate? Show your calculations. Hint: You need to consider ATP consumption for bypassed steps that may normally yield or consume AT Plasma concentration (mM)You have the task of producing 3 kilogram of porcine (pig) insulin from pig pancreases to create an emergency stockpile of insulin. You know that a typical adult pig has a 269 gram pancreas and it is possible to produce 15 micromoles of purified insulin from 1 kg of pancreatic tissue. How many fresh pig carcasses would you need to produce 3 kg of insulin?Hemoglobin molecules exposed to high levels of glucose are converted to glycated products. The glycated product used to measure blood glucose control in diabetics is hemoglobin A1C (HbA1C), contained in red blood cells that last around 3 months. In general terms, explain how HbA1C forms and why it is a useful marker for blood glucose control.
- HbA1c is a glycated hemoglobin in which a glucose molecule is covalently bound to the N-terminal valine of a hemoglobin subunit. True FalseThe enzyme chymosin secreted in calf stomachs has traditionally been used to coagulate milk to make cheese. Explain how you could produce chymosin in a bioreactor to avoid sacrificing calves for the cheese making process. Be sure to describe the process in as much detail as possible and try to mention the required tools and techniques.Human serum albumin is another protein that has an extremely long half life in the body. Due to this, the low probability event, glycation does take place. Write a rate law for this reaction: Rate = k[glucose] Rate = k[hemoglobin] Rate = k [glucose hemoglobin albumin]
- A typical multivitamin tablet can contain 2.0 mg of vitamin B2 (riboflavin), and the RDA is 0.0030 g>day. How many such tablets should a person take each day to get the proper amount of this vitamin, if he gets none from other sources?Hemoglobin glycation (so named to distinguish it from glycosylation, which is the enzymatic transfer of glucose to a protein) is a non-enzymatic process that involves reaction of the N-terminal amino group of hemoglobin and glucose. The amount of glycated hemoglobin (GHB) is usually about 5% of total hemoglobin (and corresponds to a blood glucose concentration of 120 mg/100 mL). However, in people with untreated diabetes this value may be as high as 13%, which indicates an average blood level of about 300 mg/100 mL -dangerously high. One of the aims of insulin therapy is to maintain GHB values of about 7%. Draw a possible chemical scheme for the glycation of hemoglobin.Brown and Goldstein won the Nobel Prize for discovering the molecular basis of familial hypercholesterolemia (FH). The key experiment that led to the breakthrough was that cells from FH patients responded to LDL by increasing cholesterol biosynthesis. True or False
- Unlike primates and birds, many animals possess the enzyme urate oxidase. Suggest a reason why these organisms do not suffer from gout.Many people who are lactose intolerant can eat yogurt, which is prepared from milk curdled by bacteria, without any digestive problems. Give a reason why this is possible. (Hint: Read the label on each of several yogurt containers. Do the ingredients make a difference?)Catalase is the enzyme. experiment with h2O2 3. What is the marker for the enzyme’s optimum condition?