Answered: How can we be sure that the insertion…

Science

Biology

How can we be sure that the insertion of the therapeutic gene does not harm some other necessary cell function?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter16: Reproductive Technology, Genetic Testing, And Gene Therapy

Section: Chapter Questions

Problem 12QP: In selecting target cells to receive a transferred gene in gene therapy, what factors do you think...

See similar textbooks

Related questions

Q: What is molecular pharming? Compared with the production of proteins by bacteria, why might it be…

A: The production of foreign proteins by bacteria involves selection of the desired gene, incorporation…

Q: Why do you think HIPAA was created and implemented?

A: HIPAA:It stands for: H= Health I=Insurance P =Portability A=Accountability A= Act This is a…

Q: What is the purpose of the activity “Transgenic Manipulation?”

A: Transgenic manipulation During the last couple of decades , considerable progress have been made…

Q: What is the definition of antibiotic resistance gene?

A: Antibiotics are the antimicrobial chemicals that can be bactericidal (kill the bacteria) or…

Q: Explain the Retroviral vectors of Gene Therapy ?

A: Retrovirus is used to infect the mammalian cells as they used host cells to multiply. Retrovirus is…

Q: What is the purpose of the targeting vector?

A: In molecular cloning, vector is a segment of DNA molecule, which is used as an artificial carrier of…

Q: Define the Problems with Gene Therapy Vectors ?

A: BASIC INFORMATION GENE THERAPY It is a technique used in the medical field in which there is…

Q: Do you think a U-tube could be used to distinguish betweentransduction and transformation?

A: Transformation is the process of horizontal gene transfer, where the genetic material moves from one…

Q: though the treatment of patients with ADA with gene therapy was encouraging, what is needed to…

A: Gene therapy is one of the most effective emerging methods of treatment. However, it is still not a…

Q: What is one stumbling block in AAV gene therapy in some patients?

A: Biotechnology is technology that utilizes biological systems, living organisms or parts of this to…

Q: Outline the uses of gene therapy and RNAi therapy to control genetic diseases.

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: What does the SHOX gene do?

A: SHOX gene stands for the short-stature homeobox gene. The mutation in the aforementioned gene…

Q: What are the considerations for choice of a vector in gene therapy?

A: HIV consists of single-stranded RNA in the replication form that has been transcribed into…

Q: How to use gene therapy help in the cure of COVID-19?

A: Gene therapy is a treatment for the disease in which through a gene delivery vehicle the exogenous…

Q: Define the Gene-targeting methods ?

A: Gene targeting method can be defined as the genetic engineering technique which uses the…

Q: which is the delivery techniques can bbe used to best transfer recombinant plasmids into E.coli…

A: ANSWER) The process of transferring the recombinant plasmids into the E.coli cells is called…

Q: Describe some methods used to deliver normal genes to cells for gene therapy treatments.

A: When the treatment of a disease is carried out by transferring genetic material into the cells, it…

Q: Explain gene-knockout technique.

A: According to the question, we have to provide an explanation of the gene knockout technique. So,…

Q: If your patient has a colon cancer, would you suggest trying radiation and chemotherapy instead, or…

A: Colon cancer is one of the leading causes of cancer mortality and morbidity around the world. Colon…

Q: Define the therapeutic gene?

A: Gene is a functional unit of heredity. A gene is a sequence of nucleotides in genome that codes for…

Q: Will genome editing emerge as the safest and most reliablemethod of gene therapy, rendering other…

A: Genome editing is an advanced molecular technique where the DNA sequences are altered through the…

Q: What are the two type of viral vector involved in gene therapy trials?

A: Viral vectors are the engineered tools which are used by molecular biologists to transfer genetic…

Q: Do the antibiotic-resistant mutants arise in response to the presence of the antibiotic?

A: A mutation is the alteration of the DNA sequence that changes the normal functioning of the DNA.…

Q: How Are Therapeutic Genes Delivered?

A: Therapeutic genes are those which are inserted into the body to cure the defective gene. These genes…

Q: How does phage therapy work?

A: Phages are viruses that use bacterial as hosts. Some of the phages exhibit both lytic and lysogenic…

Q: List examples of how in vivo and ex vivo gene therapy has been used to treat human disease.

A: In vivo gene therapy refers to treatment that is provided to the patient directly. The targeted…

Q: What does MEGA stand for and what is this assay used to determine? How to do perform the assay?

A: Many assisted reproductive techniques are widely used around the globe.

Q: Compare and contrast ex vivo and in vivo gene therapy as approaches for delivering therapeutic…

A: Viral vectors are used as carriers for normal genes that replace the defective genes within the…

Q: What is the difference between somatic gene therapy and germ-line gene therapy?

A: Gene is a functional unit of heredity. A gene is a sequence of nucleotides in genome that codes for…

Q: Name any one disease for which gene therapy has been proved effective?

A: Gene therapy is one of the treatment methods to treat genetic diseases. It involves the replacement…

Q: Explain how therapeutic genes may be delivered topatients

A: Human gene therapy is a successful technique that uses genes to treat and to prevent diseases. In…

Q: What are the Methods of therapeutic gene delivery?

A: Gene therapy is a promising method for correcting host pathology by the manipulation of DNA…

Q: Why is it necessary to examine gene-expression profiles, in additionto genome sequences, for…

A: Gene expression profiling is the analysis of the behaviour of thousands of genes at once to…

Q: What types of viruses are used for gene therapy, and how are they manipulated to make them useful?

A: Gene therapy is the technique used to cure or prevent the disease by introducing the normal gene in…

Q: What are the implications of resistance gene transfer for the future practice of medicine?

A: Bacteria multiply quickly and have a variety of methods for exchanging DNA. This is how they are…

Q: In selecting target cells to receive a transferred gene in gene therapy, what factors do you think…

A: Gene therapy involves transferring of cloned genes into target cells by the process of recombinant…

Q: During the first successful gene therapy trial in which Ashanti DeSilva was treated for SCID, did…

A: Gene therapy is the process by which defective or non-functional gene can be replaced by a normal…

Q: Describe the generation of multiple-drug-resistantplasmids

A: Drug inactivation or modification is one mechanism of drug resistance. Changes to the target site.…

Q: Why are viruses used in gene therapy?

A: Gene therapy is a procedure that modifies a person's genes in order to treat or cure a disease. Gene…

Q: What does silencing a gene mean?

A: Gene silencing may take place either during the translation or transcription process and it is…

Q: Explain about the enhancement gene therapy ?

A: The genes are the primary unit of life. The nucleotide sequence of the genes are responsible for…

Q: In the plaque assay, what is the precise origin of a single plaque?

A: Answer: Introduction: Virus is an intracellular infectious parasite consist of only one type of…

Q: In selecting target cells to receive a transferred gene in gene therapy, what factors do you think…

A: Gene Therapy --- Gene therapy is defined as an experimental technique in which uses of genes to…

Q: What are the potential concerns regarding the use of viral vectors in gene therapy?

A: Introduction :- Gene therapy is the process of changing the genes in your body's cells in order to…

Q: How is DNA microarray used in detecting cancer?

A: DNA or deoxyribonucleic acid is a polymer of deoxyribonucleotides connected together via…

Q: In the plaque assay, exactly what makes up a single plaque?

A: Viruses are non-cellular pathogenic particles. Viruses cannot survive on their own as they lack cell…

Q: How can gene therapy help in the cure of COVID-19?

A: Gene therapy is a therapeutic strategy that involves the introduction of gene fragments to…

Q: Which type of gene therapy involves the direct administration of viruses in patients' tissues? a.…

A: Gene therapy is an experimental technique that uses genes to treat or prevent disease. It is…

Q: Is Ivacaftor gene therapy?

A: Gene therapy is a technique used in medical field for the treatment or prevention of a disease. It…

Concept explainers

Cancer Therapy

Question

How can we be sure that the insertion of the therapeutic gene does not harm some other necessary cell function?

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Step 3

VIEW

Step by step

Solved in 3 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.

Similar questions

What's the best definition of gene therapy? a) The introduction of a non-mutated and functional gene into a patient's DNA. b) The delivery of a non-mutated and functional protein into a patient. c) The introduction of a non-mutated and functional gene into a patient's RNA. d) The delivery of drugs that encourage overexpression of a protein to compensate for a mutated protein.
In selecting target cells to receive a transferred gene in gene therapy, what factors do you think would have to be taken into account?
The nurse is explaining the general goal of gene therapy to a patient. With gene therapy, the general goal is to transfer exogenous genes to a patient for which result? a )To change the patient’s own genetic functioning to treat a given disease b )To improve drug metabolism c )To prevent genetic disorders in the patient’s future children d )To stimulate the growth of stem cells
How can we isolate stem cells and how can we use these cells in the clinic?
Answer the two parts of the question. a) Explain what gene therapy involves.b) Discuss how gene therapy can be used to treat/cure or prevent a disease and include in your answer any current challenges associated with its use.
Why has gene therapy not been the success that was expected when it was first proposed as a viable means of treating genetic disorders?
What are some possible reasons that researchers might be interested in identifying the gene that causes a genetic disease such as ICA? In other words, what benefits might result from this research?
Why is using genomic DNA in gene therapy more efficacious?
Can you explain the idea a little more? I don't fully understand how to do something. Do we need to add a new drug? Should I change the printing method of the surgical patch? How will the idea develop?
What ailment, disease, or illness urgently needs to be treated by gene therapy?
What is the difference between gene therapy and cell therapy?
I understand that microarrays are being used to define the molecular abnormality and the prognosis in some patients with leukaemia. What are microarrays?