GS-441524 is an antiviral drug. It is the active form which the antiviral prodrug remdesivir is converted into inside the body. GS-441524 has also been researched in its own right, as a treatment for feline infectious peritonitis, a lethal coronavirus disease which affects domestic cats. Which atoms(groups) in its molecule can be donors of hydrogen bond? Which atoms in its molecule can be acceptors of hydrogen bond? Is it a water-soluble compound? What is hydridization of atom C(2)? N(16)? C(10) What are the angles at atom C(5)? NH2 NH2 21 19 18 20 16 N. -N 15 13 N 14 5 -он 9н Но. Но. он он HINT: Atom N(13) is sterically unacessible and has no lone pair. 4. 3. 2.

Organic Chemistry
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Chapter21: Benzene And The Concept Of Aromaticity
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Problem 21.63P
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Is it a water-soluble compound?

GS-441524 is an antiviral drug. It is the active form which the
antiviral prodrug remdesivir is converted into inside the body.
GS-441524 has also been researched in its own right, as a
treatment for feline infectious peritonitis, a lethal coronavirus
disease which affects domestic cats.
Which atoms(groups) in its molecule can be donors of hydrogen
bond?
Which atoms in its molecule can be acceptors of hydrogen
bond?
Is it a water-soluble compound?
What is hydridization of atom C(2)? N(16)? C(10)
What are the angles at atom C(5)?
NH2
NH2
21
19
18
20
16
N.
-N
15
13 N
14
5
-он
9н
Но.
Но.
он
он
HINT: Atom N(13) is sterically unacessible and has no lone pair.
4.
3.
2.
Transcribed Image Text:GS-441524 is an antiviral drug. It is the active form which the antiviral prodrug remdesivir is converted into inside the body. GS-441524 has also been researched in its own right, as a treatment for feline infectious peritonitis, a lethal coronavirus disease which affects domestic cats. Which atoms(groups) in its molecule can be donors of hydrogen bond? Which atoms in its molecule can be acceptors of hydrogen bond? Is it a water-soluble compound? What is hydridization of atom C(2)? N(16)? C(10) What are the angles at atom C(5)? NH2 NH2 21 19 18 20 16 N. -N 15 13 N 14 5 -он 9н Но. Но. он он HINT: Atom N(13) is sterically unacessible and has no lone pair. 4. 3. 2.
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