Given the following Wild Type and Mutated DNA sequences: 1.) Identify where the base pair change occurs ( what letter changed?) 2.) For BOTH sequences, write the mRNA strands, define the codon regions and amino acid sequences. 3.) Describe what kind of mutation has occurred (missense

Human Anatomy & Physiology (11th Edition)
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Given the following Wild Type and Mutated DNA sequences:

1.) Identify where the base pair change occurs ( what letter changed?)

2.) For BOTH sequences, write the mRNA strands, define the codon regions and amino acid sequences.

3.) Describe what kind of mutation has occurred (missense, nonsense, or silent), and what effect this may have on the protein. 

 

Wild Type DNA Sequence:  3' - AGGCTCGCCTGT - 5'

Mutated DNA Sequence:    3' - AGTCTCGCCTGT - 5' 

C4GUCAGUCAGUGPO
3'
Phe
Gly
(G)
Leu
(F)
Glu
Asp (E)
(D)
(L)
Ser
(S)
Тyr
GU
Ala
(A)
A
Cys (C)
G U
Val
C
G
(V)
U
Trp (W)3.
3-
G
А С
A
C,
Arg (R)
A
A
Leu
(L)
Ser (S)
G
C
Lys (K)
A
Pro
Asn
(P)
GACUG
Gln
(N),
His
Thr
(H)
(T)
(Q)
Arg
(R)
3'
lle
(1)
Start
Stop
Transcribed Image Text:C4GUCAGUCAGUGPO 3' Phe Gly (G) Leu (F) Glu Asp (E) (D) (L) Ser (S) Тyr GU Ala (A) A Cys (C) G U Val C G (V) U Trp (W)3. 3- G А С A C, Arg (R) A A Leu (L) Ser (S) G C Lys (K) A Pro Asn (P) GACUG Gln (N), His Thr (H) (T) (Q) Arg (R) 3' lle (1) Start Stop
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