Genes a, b, and c are linked, and pairwise crosses gave the following distances: a-b 20 cM b-c 2 cM a-c 22 cM Which gene is in the middle? It's not possible to tell without additional information.
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- QUESTION 3 Linkage disequilibrium is defined by which of the following? O Positions in the genome where people vary by a single nucleotide base O The occurrence of two alleles in the repulsion configuration O The probability that two genes are linked O Crossing over that occurs between two genes that are located close to each other O The nonrandom association between alleles in a haplotype QUESTION 4 Red-green color blindness is a human recessive X-linked disorder. A young man with a 47, XXY karyotype (Klinefelter syndrome) is colorblind. His mother and father have normal color vision, but his mother has a father who is colorblind Did the nondisjunction event that gave rise to the young man with Klinefelter syndrome happen in the mother, the father or is it impossible to tell (assume that no crossing over took place in prophase I of meiosis)? a. Mother b. Father c. Impossible to tell Did this nondisjunction happen during Meiosis I, Meiosis II, or is it impossible to tell? a. Meiosis I…QUESTION 6 In Drosophila, sepia eyes (se) and stubble bristles (sb) are recessive to the wildtype eyes and bristles (se* and sb+). A female heterozygous for both genes was test crossed to a male homozygous recessive for both genes. The progeny of this cross are given below: Phenotypes wildtype eyes and wildtype bristles (set, sbt) # of Progeny 334 widltype eyes and stubble bristles (set, sb) 162 sepia eyes and wildtype bristles (se, sb+) 158 sepia eyes and stubble bristles (se, sb) 346 What is the genetic distance (in map units) between these two genes? Are the alleles in the heterozygous female in the cis (coupling) or trans (repulsion) conformation? Are the two genes in this problem unlinked, completely linked or incompletely linked?Question #1 a. Explain why there is a non-Mendelian 2:1 yellow/agouti phenotypic ratio in this cross. b. What is the Raly gene? What does it encode? How does it relate to the lethality of Ay? c. A heterozygous mouse AAy does not produce enough pigment and it is yellow. Homozygous individuals die during development, but AAy heterozygous do not. Why? You may use any graphic aid to explain this, if necessary. This means that you may use a Punnett square or a forking segregation diagram, or computations with fractions.
- QUESTION 2 A researcher crosses mice with brown eyes and short tails, and the F1 progeny were recovered in the following numbers and phenotypic classes: F1: 32 apricot, short : 30 brown, long : 139 brown, short : 9 apricot, long You know the genes encoding these traits are autosomal, completely dominant and assort independently. You want to use a chi-square test to analyse these results. a) Give the expected number of individuals in the "brown, short" class. b) What is your null hypothesis for the chi-square test? c) You obtain a value of 8.59 for the chi-square test. What conclusion can you make from the results of the chi-square test? d) Making use of the appropriate genetic convention for naming alleles, give the genotype of any of the progeny in the "apricot, short" class. df 0.995 0.975 0.9 0.5 0.1 0.05* 0.025 0.01 0.005 1 0.000 0.000 0.016 0.455 2.706 3.841 5.024 6.635 7.879 2 0.010 0.051 0.211 1.386 4.605 5.991 7.378 9.210 10.597 0.072 0.216 0.584 2.366 6.251 7.815 9.348 11.345…QUESTION 1 In pea plants, round (R) is dominant to wrinkled (r), yellow (Y) is dominant to green (y), and tall (T) is dominant to short (t). A homozygous round, heterozygous yellow, short pea plant is crossed with a wrinkled, heterozygous yellow, heterozygous tall plant. Show the branching diagram, along with the probabilities of all genotypes. What is the probability (show work) and phenotype of the following genotype: Rryytt. Attach FileQuestion 10 of 18 Attempt 10 Suppose a geneticist uses a three-point testeross to map three recessive, linked hummingbird wing-shape mutations called tk, f, and s, where tk is associated with thick wings, f is associated with flat wings, and s is associated with sharp wings. He first crosses homozygous sharp birds to homozygous thick, flat birds. Next, he testcrosses the Fi progeny to thick, flat, sharp birds. He obtained the results shown. Given this data, label the progeny phenotypic classes as either parental, single crossover (SCO), or double crossover (DCO) recombinant types. Each label may be used multiple times. Two classes have already been filled in. Phenotype Number Recombinant type sharp 819 Answer Bank thick, flat 821 SCO DCO flat 183 parental thick, sharp 169 SCO thick 6. flat, sharp thick, flat, sharp 28 SCO wild type 26
- QUESTION 16 A series of two-point crosses were carried out among seven loci (a, b, c, d, e, f and g), producing the following recombination frequencies. Map the seven loci, showing their likage groups, the order of the loci in each linkage group, and the distances (in map units) between the loci of each group. Use the example given below for how you should format your answer. Your answer may have more or fewer linkage groups. Please format your answer as in the map of mutants o-u below (note: your answer may contain a different number of linkage groups): Linkage group 1: 0_12mu P 4mu_Q8mu Linkage group 2: S Linkage group 3: U 7mu T R Loci a and b % Recombination 50 a and c 50 a and d 50 a and e 50 a and f 50 a and g 50 b and c 50 b and d 35 b and e 50 b and f 50 b and g 50 c and d 50 c and e 24 c and f 50 c and g 10 d and e 50 d and f 20 d and g 50 e and f 50 e and g 15 fand g 50QUESTION 6 Assume that a researcher is studying coat color in voles. Three strains of white vole have been isolated: milky, blanc, and weiss. White is a recessive trait in each strain. Homozygous white voles are obtained for each strain. Consider the following crosses: milky X weiss = all white progeny (mutant) milky X blanc = all brown (wild-type vole color) blanc X weiss = all brown (wild-type vole color) The conclusion most consistent with these results is O A all three strains have mutations in the same gene. O B. all three strains have mutations in different genes. OC. milky and blanc have mutations on the same gene, weiss has a mutation in a different gene. D. milky and weiss have mutations on the same gene, blanc has a mutation in a different gene. O E. weiss and blanc have mutations on the same gene, milky has a mutation in a different gene.Question- QUESTION 1 Consider three linked genes: A, B, C. Percent recombination between gene B and C is 11% and no crossing over occurs between A and B. If a heterozygote in cis conformation is test crossed, what is the probability of an offspring with the genotype AaBbcc? A. 0.011 B. 0.055 C.0.022 D.0.089 E. 0.045
- Question 9 Consider that a certain gene is a maternal effect gene and that the allele for dark brown pigment is incompletely dominant to the allele for no pigment (white). The incomplete dominant phenotype is light tan. If a heterozygous female is crossed with heterozygous male, what will be the phenotypic ratio of the progeny? A) 1 dark brown: 2 light brown: 1 white. B) 3 dark brown: 1 white C). all dark brown D) all light tan E) cannot be determined CS Scanned with CamScannerQUESTION 3 In Drosophila, miniature wings (X) result from an X-linked allele that is recessive to the allele for long wings (X). Give the most likely genotypes of the parents in each of the following crosses: Male Parent Female Parent Cross #1 Cross #2 Long Miniature Genotype for male parent #1: Genotype for female parent #1: Genotype for male parent #2: Genotype for female parent #2: Long Long Male Offspring 231 Long 250 Miniature 420 long 417 Miniature Female Offspring 560 Long 0 Miniature 412 Long 415 Miniature Use Xm and X+ for the allele symbols in your answers as there is not a superscript option. Also, remember that males are hemizygous!Question 1: In tomatoes, round fruit (O) is dominant to oblong fruit (o). Write as much as possible of the genotypes of: (A) A plant from a homozygous round-fruited stock (B) A plant from an oblong strain (C) A round-fruited plant which resulted from a testcross (D) A oblong-fruited plant which resulted from the cross of two round-fruited ones.