Explain the Mechanisms and pathways of CCL22, SERPINE1, TIMP1, CX3CL1 genes to adenocarcinoma tumours in regards to bowel cancer. Provide evidence.
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A: INTRODUCTION Answer of question 1 & 2 guven below.
Explain the Mechanisms and pathways of CCL22, SERPINE1, TIMP1, CX3CL1 genes to adenocarcinoma tumours in regards to bowel cancer.
Provide evidence.
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- Explain What are the advantages and disadvantages of CCL22, SERPINE1, TIMP1, CX3CL1 genes to adenocarcinoma tumours in regards to bowel cancer. Provide evidence.explain how do the CIN MSI CIMP pathways all link together in develpment of adenocarcinoma tumours colorectal cancer. Give full explanation if there do or do not link.Describe the targeting disease and the mechanism of action for Cetuximab (EGFR)
- What is the importance of inflammatory response genes in adenocarcinoma tumours in regards to bowel cancer. what are there benefits. what are there roles. provide detailed analyse wiht exmaples and evidence.Suggest a mode of action for fluorouracil in cancerchemotherapy.A 61-year-old female with KRAS wild- type metastatic colon cancer was initially treated with FOLFOX. After 6 months of chemotherapy, she experienced a partial response to treatment and therapy was continued. Four months later, she developed worsening abdominal pain and an abdominal CT scan showed new sites of disease in her liver. Her oncologist changed her treatment regimen to FOLFIRI plus bevacizumab. Two months later, imaging studies show an increase in the size and number of liver metastases. Which of the following modifications to her current treatment regimen is now most appropriate? Select one: a. Discontinue current regimen; start irinotecan plus cetuximab b. Discontinue current regimen; start FOLFOXIRI plus panitumumab c. Continue FOLFIRI and bevacizumab; add cetuximab
- explain and proivde anylyses what are the diagnoses and current and potential future treatments for adenocarcinoma tumours colorectal cancer (colon). And Make linkadge too CIN, MSI, CIMP pathways. Give detailed examples of treatments for the disease.What is the importance ofKRAS gene in the development of colorectal cancer. ?Explain the multi hit approach to colorectal cancer regarding the pathways CIN chromosomal instability (CIN), microsatellite instability (MSI). explain step by step. what genes are involved.
- propose a biomaterial-based drug delivery system for carrying targeted delivery of doxorubicin for the specific treatment of hepatocellular carcinoma via intravenous route (for human)Explain several ways by which the treatment of cancer by che-motherapy may temporarily create additional health problemsfor the patient.explain the advanatges and disadvanatges of the importance of inflammatory response genes in CIN, MSI, CIMP pathways that are involved in regards to adenocarcinoma tumours colorectal cancer (colon) Provide detailed analysis with examples.