Each of the three reactions below shows a Grignard reagent reacting with an unknown electrophile (1, 2 and 3) in the solvent diethyl ether to produce a product. All products are neutralized with HCl at the end of the reaction. Select the electrophiles from the list below that correspond to the reactions shown below: Drag and drop options on the right- hand side to reorder and match with items on the left. Reordering may cause items on the right-hand side to swap positions. (1) ii (2) vi (3) iv vii V ii
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
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