e. Show the products of the hydrolysis of the following tetrapeptide at physiological pH by applying the generic reaction hydrolysis of an amide shown below. (How many separate products should you have?) Label the N-terminus and C-terminus the peptide. Lov Tetrapeptide H₂N +1O4 H₂C CH₂ FE NH NH "NH₂ NH₂ NH 'OH OH +

Chemistry: Principles and Reactions
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Chapter23: Organic Polymers, Natural And Synthetic
Section: Chapter Questions
Problem 31QAP: On complete hydrolysis, a polypeptide gives two alanine, one leucine, one methionine, one...
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e. Show the products of the hydrolysis of the following tetrapeptide at physiological pH by applying the
generic reaction hydrolysis of an amide shown below. (How many separate products should you have?)
Label the N-terminus and C-terminus the peptide.
Tetrapeptide:
H₂C.
H₂N
CH₂
NH
"NH₂
NH
NH₂
NH
HOTH
H₂C 'OH
OH
+
Question #5:
Look at the structures of the products you drew in answering problems # 2a, # 3a and #4a. Which of these
three biomolecules would you expect to be the most water-soluble? Explain. Be as specific as you can.
(You DO NOT have to draw pictures showing the interactions.)
**Remember that you have to discuss the solubility of all three in order to explain why one might be more
soluble than the other two.
Transcribed Image Text:e. Show the products of the hydrolysis of the following tetrapeptide at physiological pH by applying the generic reaction hydrolysis of an amide shown below. (How many separate products should you have?) Label the N-terminus and C-terminus the peptide. Tetrapeptide: H₂C. H₂N CH₂ NH "NH₂ NH NH₂ NH HOTH H₂C 'OH OH + Question #5: Look at the structures of the products you drew in answering problems # 2a, # 3a and #4a. Which of these three biomolecules would you expect to be the most water-soluble? Explain. Be as specific as you can. (You DO NOT have to draw pictures showing the interactions.) **Remember that you have to discuss the solubility of all three in order to explain why one might be more soluble than the other two.
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