During the decarboxylation of acetoacetate, what is the nucleophile and what is the electrophile? Is the formation of a schiff base simply a preparation step or is the formation of a schiff base formed also by nucleophile/electrophile interaction? CO₂H+Love 2 [onfron] I ow-t-ons[CH₂]ciCH3-C-CH₂CH3-C=CH3-C-CH3AcetoacetateOH-RNH₂CH3-C-CH20:EnolateAcetoacetate decarboxylaseCO₂H+Figure 11-11©2013 John Wiley & Sons, Inc. All rights reserved.RCH3-C=CH₂inSchiff base Electrophile(imine)RNH2Acetone-OHHCH3-C-CH3

Electrophile:- Electrophiles are electron deficient species and can accept an electron pair from…

During the decarboxylation of acetoacetate, what is the nucleophile and what is the electrophile? Is the formation of a schiff base simply a preparation step or is the formation of a schiff base formed also by nucleophile/electrophile interaction?

During the decarboxylation of acetoacetate, what is the nucleophile and what is the electrophile? Is the formation of a schiff base simply a preparation step or is the formation of a schiff base formed also by nucleophile/electrophile interaction?

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter20: Carboxylic Acids And Nitriles

Section20.8: Spectroscopy Of Carboxylic Acids And Nitriles

Problem 15P: Cyclopentanecarboxylic acid and 4-hydroxycyclohexanone have the same formula (C6H10O2), and both...

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Concept explainers

Aldehydes and Ketones

Aldehydes and ketones are organic compounds that have a carbonyl group, C = O, as their functional group. They both differ in the placement of this carbonyl group in their structures.

Question

CO₂
H+
Love 2 [onfron] I ow-t-ons
[CH₂]
ci
CH3-C-CH₂
CH3-C=
CH3-C-CH3
Acetoacetate
OH
-RNH₂
CH3-C-CH2
0:
Enolate
Acetoacetate decarboxylase
CO₂
H+
Figure 11-11
©2013 John Wiley & Sons, Inc. All rights reserved.
R
CH3-C=CH₂
in
Schiff base Electrophile
(imine)
RNH2
Acetone
-OH
H
CH3-C-CH3

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