Dimethoate is a commonly used agrochemical. However, chronic exposure to it can cause an individual to develop hyper-ß-alaninemia (i.e., excessive alanine) in the muscles. Would hyper-ß-alaninemia impact glycolysis? O Yes, pyruvate kinase would be suppressed as a consequence of hyper-B-alaninemia. Yes, glucokinase would be suppressed as a consequence of hyper-ß-alaninemia. No, hyper-ß-alaninemia would not impact glycolysis. Yes, hexokinase would be suppressed as a consequence of hyper-ß-alaninemia. O Yes, phosphofructokinase would be suppressed as a consequence of hyper-B-alaninemia.
Q: Given the graph below, what changes to % saturation of hemoglobin would you expect from the change…
A: Hemoglobin is a tetrameric protein, each subunit contains heme prosthetic group. One hemoglobin…
Q: Which specific carbohydrate has the following characteristics: 1) Most abundant monosaccharide in…
A: Carbohydrate is a class of organic compounds found in living tissues and foods as starch, cellulose,…
Q: Glucose oxidase [S] (glucose, mM) 0.1 5 7 8 15 20 0.2 0.4 0.5 1.0 2.0 3.0 5.0 7.5 35 45 55 60 80 90…
A: Enzymology relies on the fundamental idea of Michaelis-Menten kinetics. It covers the interactions…
Q: In one type of hemoglobin variant, lysine EF6 is replaced by an aspartic acid residue. What would be…
A: The replacement of lysine (K) by aspartic acid (D) at position EF6 in hemoglobin affects the…
Q: From the peptide chain: Met-Tyr-Phe-Arg-Ile-Glu-Asn-Asp-Ser, draw the structure of the product…
A: There are four types of biological macromolecules: proteins, nucleic acids, lipids and…
Q: What would be the effect on the activity of phosphofructokinase of the mutation of Asp103 to the…
A: Based on the type of effect brought about on the activity of a protein, mutations can be of 3 types.…
Q: The protein fragments ABS1 and ABS2 of tropomodulin were produced as fusion proteins with chitin…
A: It is possible to filter proteins or fragments of proteins which have been fused with a…
Q: Discuss the major challenges when using microarray techniques to study differential gene expression.…
A: Microarray is a powerful laboratory technique used in genomics and molecular biology to…
Q: 19. Draw all 20 of the genetically encoded amino acids at (a) pH = 1; (b) pH = 1; (c) pH = 12.…
A: Amino acids are organic compounds that form the building blocks of proteins in cells. The structure…
Q: All of the following statements about glucose are true except: Glucose is metabolized in the…
A: Glucose is a simple sugar (monosaccharide) that serves as a primary source of energy for living…
Q: For each Acetyl CoA that enters the Krebs Cycle and the products goes through the ETC…
A: The Krebs Cycle, also known as the citric acid cycle, is a crucial component of cellular…
Q: An enzyme can organize substrates to be nearby in such a way where the local/nearby concentration of…
A: Catatalysis is a phenomenon in which the rate of reaction is altered with the help of a substance…
Q: fertilizers
A: In various regions with distinct geographic characteristics, fertilizers containing zinc have been…
Q: Which of the following is TRUE? Chylomicrons have more triglycerides than HDLs. HDL carries both…
A: In the human body, lipoproteins are essential for lipid transport and metabolism. The equilibrium of…
Q: A protein with a molecular weight of about 12,000 Da was isolated in elevated quantities from cells…
A: A peptide is chain of amino acid sequences linked together via a peptide bond. The amino acid…
Q: The protein catalase is an enzyme that catalyzes the decomposition of hydrogen peroxide: 2 H2O2 (aq)…
A: For a one-substrate enzyme reaction, the Michaelis-Menton equation shows the quantitative…
Q: What is the secondary structure of the peptide hormone GLP-1
A: GLP-1 (glucagon-like peptide 1) is a peptide hormone that is essential to control blood sugar…
Q: Myoglobin would be an inappropriate carrier of oxygen to peripheral tissues because: Myoglobin…
A: Hemoglobin and Myoglobin are two oxygen binding proteins found in mammals. Myoglobin is an oxygen…
Q: Draw the linear fisher projections of D-ribarnic acid, L-xyluronic acid, D-arabinuronic acid,…
A: Carbohydrates are polyhydroxy aldehydes or ketones. They can be classified as monosaccharides,…
Q: Single stranded DNA fragment of M13 phage DNA shown was mixed with the following primers P1: AGTAG…
A: Polymerase chain reaction also abbreviated as PCR.A specific DNA fragment is quickly multiplied…
Q: You run a series of assays at 25°C on enzyme A. You measure the velocity for a range of S…
A: This question can be solved using Lineweaver Burk plot. This graph also represents the enzyme…
Q: A membrane simulator is shown below. Watch the video clip in order to answer the question. Diffusion…
A: Diffusion is very important process of nature where substances present in excess amount will move…
Q: Why is control of column and detector temperature more important for non- suppressed IC (Ion…
A: The control of column and detector temperature is a fundamental aspect of ion chromatography (IC), a…
Q: A membrane simulator is shown below. Watch the video clip in order to answer the question. Diffusion…
A: Osmosis is the movement of water molecules across a semipermeable membrane, driven by the difference…
Q: Identify the species that are liganded to the porphyrin ring Fe(II) ion in deoxyhemoglobin (i.e., Hb…
A: The protein haemoglobin, which is present in red blood cells, is essential for the movement of…
Q: An allosteric enzyme that follows the concerted mechanism (MWC model) has a T/R ratio of 300 in the…
A: Allosteric enzymes contain an extra binding site for effector molecules in addition to the active…
Q: What is the process of beta oxidation
A: Beta-oxidation is a metabolic process that occurs in the mitochondria of cells and is responsible…
Q: 1) Phosphatidate composed of octadecanoate fatty acids 2) Phosphatidate composed of hexadecanoate…
A: The graph given below shows the fluidity of membrane. The degree of bilayer fluidity depends on…
Q: A protein which has more than one stable conformation is called a: a) chaperone protein b) molten…
A: There are three classes of biological macromolecules: proteins, nucleic acids, lipids and…
Q: R + FAD SCOA acyl-CoA dehydrogenase R + SCOA FADH 2
A: A class of enzymes known as acyl-CoA dehydrogenases (ACADs) is responsible for catalysing the first…
Q: Which amino acid residue would be most effective at forming a strong intermolecular interaction with…
A: Amino acids have chemically diverse side groups that can participate is different types of…
Q: Classify the phrases. Does each phrase describe a kinase, a phosphatase, neither, or both? Kinases…
A: A cell deploy different strategies to regulate the activity of enzymes. One such strategy is to add…
Q: A scaffold protein can serve as a platform to accommodate a collection of enzymes involved in…
A: Scaffold proteins can serve as a platform to accommodate multiple enzymes involved multi-step…
Q: 3.) The enthalpy change associate with a biological process is -13200 cal/mol at 298K and +14700…
A: The heat capacity of a system is the amount of heat that must be supplied to a system to raise its…
Q: What are enzymatic markers within the mitochondria of oxidative metabolism
A: Mitochondria is the membrane-bound organelle. Mitochondria is the powerhouse of the cell. It plays a…
Q: Substrate concentration how reaction rate (velocity) varies with substrate concentration. Rate…
A: Enzyme is usually a protein that catalyzes a reaction by increasing the rate or the velocity of the…
Q: 3. (a) The (acid) Bohr effect is defined as the up- take of protons by hemoglobin molecules at pH ≤…
A: The picture displays the deoxyhemoglobin (deoxyHb) oxygen dissociation curves (ODCs) for humans and…
Q: rostaglandin synthase converts which molecule into prostaglandin H2? ____________ Movement of a…
A: The biological membrane that surrounds a living cell is called the cell membrane. The structure of…
Q: PEGylation plays an important role in the formulation of nanoparticle-based therapeutics: mark all…
A: PEGylation is a process in which polyethylene glycol (PEG) molecules are covalently attached to…
Q: In the article the authors reference the canonical forces in protein folding. Describe how these…
A: As per the central dogma of molecular biology, the DNA contain the information needed to synthesize…
Q: A researcher was studying red blood cells from a patient homozygous for the sickle cell mutation in…
A: In sickle cell anemia, a genetic condition, red blood cells can become deformed and "sickle-shaped"…
Q: How many co2 are produced from 1 glucose and 1 c16 fatty acid?
A: During the process of cellular respiration, one glucose molecule breaks down into six carbon dioxide…
Q: How does Foldit Protein Folding Game use puzzles like Design, De Novo, Revisiting, help in…
A: The Department of Biochemistry and the Center for Game Science at the University of Washington…
Q: A peptide in a solution with a pH of 7 has the following sequence: K-R-E-D-H-D-E…
A: The isoelectric point (pI) is the value of pH at which molecule carries no charge or the net charge…
Q: You discover a protein that displays improved catalytic efficiency. Would you predict that this…
A: Catalytic efficiency, can be defined as a measure of how efficiently an enzyme converts substrates…
Q: In the scenario shown above, the green spheres are Glucose molecules and the blue dots are water…
A: Note:- sorry as per the honor code we are not allowed to refer to external links, However, we will…
Q: 1. Start with the Michaelis-Menten equation and convert it to a double-reciprocal equation. Show how…
A: For a one-substrate enzyme-catalyzed reaction, the Michaelis-Menton equation shows the quantitative…
Q: In the presence of oxygen, most living cells make ATP by oxidative phosphorylation, which takes…
A: a.the given chemical equation is- An…
Q: how do telomeres protect against replicative shortening
A: Telomeres occur as repetitive regions found towards the end of a chromosome. Telomeres occur in a…
Trending now
This is a popular solution!
Step by step
Solved in 3 steps
- What type of regulation would be expected when anaerobic metabolism is occurring in the muscle? Select all that apply. O Activation of pyruvate dehydrogenase kinase O Increased levels of calcium to activate pyruvate dehydrogenase phosphatase O Phosphorylation of pyruvate dehydrogenase O Inhibition of pyruvate dehydrogenase complex O Increased levels of NADH to activate citrate synthase O Increased levels of NADH to inhibit alpha-ketogluterate dehydrogenase complex O Increased levels of acetyl CoA to activate pyruvate carboxylase for gluconeogenesisWhich of the following is TRUE? O Both AMP and ADP are negative regulators of glycogenolysis. ATP shifts the curve of glycogen phosphorylase to the left. O Citrate binds covalently to acetyl CoA carboxylase. Phosphofructokinase-1 is an allosterically regulated enzyme in glycolysis. The carnitine shuttle is positively regulated by Malonyl CoA.To begin the TCA cycle, pyruvate must be converted into acetyl-Coenzyme A (acetyl-CoA) by the enzyme complex of pyruvate dehydrogenase. This complex requires 5 different coenzymes to function properly. What are they?
- A patient exhibiting all the symptoms of beriberi is placed on a thiamine-enriched diet; however, the symptoms do not disappear. Genetic screening suggests a defect in pyruvate dehydrogenase phosphatase. Briefly explain why the genetic defect caused beriberi symptoms andy why thiamine supplementation had no effect.In the pyruvae dehydrogensae complex, acetyl-coa is released by the dihydrolipoyl transacetylase activity. What is the purpose of the following enzymatic activity.Which of these are components of animal fatty acid synthase (FAS)? ✔B-ketoacyl reductase enoyl reductase acetyl transacylase acyl CoA synthetase 3-hydroxyacyl dehydratase acyl CoA dehydrogenase Incorrect Fatty Acid Synthase (this diagram based on fungal FAS)
- I still struggle to understand the link between beta-oxidation and ketogenesis pathways. So under low glucose condition, cell will not be able to run glycolysis but instead gluconeogenesis to make glucose, so citric acid cycle will also be reduced because there is not enough acetyl CoA to combine with oxaloacetate, thus leading to Increases beta oxidation to break down fatty acids for acetyl CoA production. Then why can't acetyl CoA be used directly from here for TCA but through ketone bodies? Furthermore, what conditions lead to activation for the production of ketone bodies, and during that production does it recycle CoA, and if so, what pathway will that CoA be used for? Finally, when ketogenesis occurs, how are other pathways affected (glycolysis, gluconeogenesis, capacity of TCA, CoA availability, beta oxidation, glucose take up by liver cells?How similar of an effect would a mutation in pyruvate dehydrogenase have, compared to a mutation in pyruvate carboxylase that blocks its ability to be regulated by acetyl-CoA?Fructose-2,6-bisphosphate is an activator of and an inhibitor of O phosphofructokinase; hexokinase O fructose bisphosphatase; phosphofructokinase O phosphofructokinase; fructose bisphosphatase O glucose-6-phosphatase; pyruvate kinase O pyruvate kinase; phosphoenolpyruvate carboxykinase
- Which of the following is NOT a fate of pyruvate in metabolism? .. Conversion to alanine as its storage form or for use by peripheral tissues such as skeletal muscles. Conversion to acetyl CoA for complete oxidation in the TCA cycle. Conversion to oxaloacetate in gluconeogenesis Conversion to lactate in a completely anaerobic process. L. Conversion to phophoenolpyruvate for the synthesis of glucoseWhat is(are) the only active site(s) not used in the second round of fatty acid synthase? Select all that apply. Group of answer choices Acetyl-CoA ACP Transacylase Beta-Ketoacyl- ACP Synthase Beta-Ketoacyl- ACP Dehydrase Palmitoyl thioesterase Malonyl-CoA ACP Transacylase Enoyl-ACP ReductasePyruvate dehydrogenase catalyzes the conversion of pyruvate to acetyl CoA. In this reaction, one molecule each of the catalytic coenzymes TPP, FAD and lipoamide participate in the reaction but are not consumed. OTrue O False