Compare and contrast SN1, SN2, El and E2 reactions. What are some obvious similarities and differences between each reaction pathway? What are the requirements for each reaction to work? Discuss why SN2 is in direct competition with E2 while SN1 is in direct competition with the E1 reaction pathway. What is the rate expression for each? Which reactions are concerted? Which reactions are step-wise? Which reactions are stereospecific and what is the stereospecificity of each that are? How do the variables below help influence which reaction pathway will lead to the major product formed? a. Substrate (substitution pattern and leaving group ability) b. Nucleophile/base strength (weak or strong) and size (unhindered or hindered) c. Solvent (polar-aprotic or polar-protic) d. Temperature (low/ambient temps vs. higher temps)

Compare and contrast SN1, SN2, El and E2 reactions. What are some obvious similarities and differences between each reaction pathway? What are the requirements for each reaction to work? Discuss why SN2 is in direct competition with E2 while SN1 is in direct competition with the E1 reaction pathway. What is the rate expression for each? Which reactions are concerted? Which reactions are step-wise? Which reactions are stereospecific and what is the stereospecificity of each that are? How do the variables below help influence which reaction pathway will lead to the major product formed? a. Substrate (substitution pattern and leaving group ability) b. Nucleophile/base strength (weak or strong) and size (unhindered or hindered) c. Solvent (polar-aprotic or polar-protic) d. Temperature (low/ambient temps vs. higher temps)

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter14: Elimination

Section: Chapter Questions

Problem 20E

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