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can you tell me what group of viruses (groups 1-7) each image represents and explain how you know?
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- ss (-) RNA viral genome RNA polymerase RNA-dependent # O dsRNA O dsDNA. RNA-dependent RNA polymerase Coples (-) RNA strand transcription Copies (-) RNA strand. 80 ss (+) RNA S5 FA viral translation protein (+)RNA (viral mRNA) RNA-dependent RNA polymerase Copies (+) RNA strand. What type of virus is replicating in the picture? (-)ssRNA (+)ssRNA % C wil ss (-) RNA viral genome <(C 16 & 7a) What is the main structural and functional difference between microbial opsins and mammalian opsins? b) Give one example to each group. c) Why does the discovery of those microbial opsins become a major breakthrough in neuroscience? Edit Format TableMake sure you have at minimum watched the WK11 Concepts in Context videos on Spinal Muscular Atrophy. Spinal Muscular Atrophy: “Mechanism of Splicing Regulation of Spinal Muscular Atrophy Genes” (2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026014/ Abstract: “Spinal muscular atrophy (SMA) is one of the major genetic disorders associated with infant mortality. More than 90% cases of SMA result from deletions or mutations of Survival Motor Neuron 1 (SMN1) gene. SMN2, a nearly identical copy of SMN1, does not compensate for the loss of SMN1 due to predominant skipping of exon 7. However, correction of SMN2 exon 7 splicing has proven to confer therapeutic benefits in SMA patients. The only approved drug for SMA is an antisense oligonucleotide (Spinraza™/Nusinersen), which corrects SMN2 exon 7 splicing by blocking intronic splicing silencer N1 (ISS-N1) located immediately downstream of exon 7. ISS-N1 is a complex regulatory element encompassing overlapping negative motifs and…
- 11 111 FLATRON WIS songs to listen to on a late n (1) Messenger f 253282375 390061782796379 8 x ++ Scontent.fmnl17-4.fna.fbcdn.net/v/t1.15752-9/253282375 390061782796379 8678836692018933574_n.jpg?_nc_cat3D105&ccb%3D1-5&_nc_sid=Dae9488&_nc_eui2=DAeERUdQ E Apps Discussion Questions (answer these questions on a separate sheet of paper) 1. Explain how hCG secretion is regulated. Is it secreted by a pregnant woman or her offspring? 2. hCG depresses some reactions of the immune system. What adaptive advantage do you think this has? Ac P Type here to search LGWould the following alterations to Src be oncogenic? Explain. (a) The deletion or inactivation of the SH3 domain. (b) The mutation of Tyr 416 to Phe.what general features may make the C3b receptor suitable for binding C3b but not other ligands?
- Synaptic vesicles release into the synapse to give the message to the post synaptic neuron?Multicellular organisms:a) are larger in size than unicellular organisms b) can do a wider variety of functionsFor a stroke patient with hypertension who is a candidate for recombinant tissue plasminogen activator rt pa which blood pressure control strategy is appropriate?The S (spike) glycoprotein of coronaviruses can engage receptors by the N-terminal domain, the C-terminal domain, or both. The C-terminal domains of both human SARS coronaviruses bind ACE2 (angiotensin-converting enzyme 2), whereas that of MERS-CoV binds DDP4 (dipeptidyl peptidase 4). In contrast, in mouse hepatitis coronavirus (MHV) the N-terminal domain of S binds CEACAM (cell adhesion molecule 1). You have identified a novel coronavirus with an S protein that displays similarity to MHV at the N terminus and to SARS at the C terminus. What are the molecules most likely to function as receptors and how will you test this?You work for a large biotechnology company that is studying viruses, vaccines, and small molecule inhibitors. You are asked to give an overview of cell signaling as it relates to the coronavirus and young adults. a) Describe cell signaling pathways (e.g., at least 3) that are likely manipulated during a coronavirus infection. In your description, include how the pathways are involved in antagonizing the host antiviral response.
- 1. Precise words:Find the nonspecific terms in the following sentences. Replace the nonspecific choices with more preciseterms or phrases (It is not necessary to change the sentence structure).(i) All OVE mutants showed enhanced iP concentrations.(ii) Plants were kept in the cold overnight.(iii) To provide proof of concept for our hypothesis, we studied a virus in its host cell.(iv) The present paper reports on continuing experiments that were performed to clarify thissurprising effect.(v) The first transition state is a little lower in energy than the second transition state. 2. Simple words:Improve the word choice in the following examples by replacing the underlined terms or phrases withsimpler word choices (do not change the sentence structure).(i) These data substantiate our hypothesis.(ii) The difference in our results compared to those of Reuter et al. (1995) can be accounted forby the fact that different conditions were used.(iii) For the purpose of discussing cell migration we…7. Fill in the table below, outlining different aspects of glutamate singlaing in the mammalian brain. A legend of possible entries is provided below the table, specifically for the columns "marker genes", “associated G proteins" and "ionotropic targets" Marker gene Ionotropic receptors Possible associated G proteins Gs Gą G₁/Go Possible marker genes: Choline acetyltransferase Solute carrier family 17 Glutamate decarboxylase Dopamine ß hydroxylase Possible ionotropic targets: Cayl channels Cav2 channels GIRK channels M-type K¹ channels BK channels SK channels Metabotropic Associated receptors G protein mGluR 1,5 mGluR 2-4,6-7- Pre- or post- Ionotropic Neuronal effects synaptic action? target(s) Tryptophan hydroxylase 2 Tyrosine hydroxylase Histidine decarboxylaseDefine α6β4 integrin