Calculate the weight in grams of a double-helical DNA molecule stretching from the Earth to the Moon (320000 km). Assume that the DNA double helix weighs 1 x 10-18 g per 1000 nucleotide pairs and that each base pair extends 3.4 Å weight:
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- There is one base pair for every 0.34 nm of DNA and the totalcontour length of all the DNA in a single human cell is 2 m.Calculate the number of base pairs in a single cell. Assumingthat there are 1014 cells in the human body, calculate the totallength of DNA. How does this estimate compare to the distance from the earth to the sun (1.5 * 108km)?The figure shows that the average distance between base pairs measured parallel to the axis of a DNA molecule is 3.4 Å. The average molar mass of a pair of nucleotides is 650 g•mol-1. Estimate the length in cm of a DNA molecule of molar mass 5.1x109 g•mol-1. 4.0 cm Roughly how many base pairs are contained in this molecule? 4.0 7.1e6 X base pairs AT CG OH O-P=D0 G C TA Adenine Thymine OH CH2 N-H.......O CH3 H -N N..... G C H A Он C G G C TA AT OH CH2 Cytosine Guanine H. O.......H-N H H' H N…**H-N HLH O N-H..... H2C OH TA OH CH2 (b) The most common structure of DNA, which is a right-handed double helix. The two strands are held together by hydrogen bonds and other intermolecular forces. (a) Base-pair formation between adenine (A) and thymine (T) and between cytosine (C) and guanine (G).Calculate the weight in grams of a double-helical DNA molecule stretching from Earth to the moon (~320,000 km). The DNA double helix weighsabout 1 × 10−18 g per 1,000 nucleotide pairs; each base pair extends 3.4 Å. For an interesting comparison, your body contains about 0.5 g of DNA.
- The figure shows that the average distance between base pairs measured parallel to the axis of a DNA molecule is 3.4 Å. The average molar mass of a pair of nucleotides is 650 g•mol-1. Estimate the length in cm of a DNA molecule of molar mass 5.1x109 4.0 .26 g•mol-1. cm Roughly how many base pairs are contained in this molecule? [4.0 784615 x base pairs CG G C OH TA Thymine Adenine H. H. OH CH2 N-H.......O CH3 H H N……·H–N HLH TA OH 0-P H2C CG G C H. CH2 Guanine H OH Cytosine ... H-N TA AT H' N.....H-N HLH N-H.......O H2C OH H -o. -P3D0 TA 0- OH H. -CH2 (b) The most common structure of DNA, which is a right-handed double helix. The two strands are held together by hydrogen bonds (a) Base-pair formation between adenine (A) and thymine (T) and between cytosine (C) and guanine (G). and other intermolecular forces.Assume the energy of hydrogen bonds per base pair to be 5.86 kJ•mol-1. Given two complementary strands of DNA containing 145 base pairs each, calculate the ratio of two separate strands to hydrogen-bonded double helix in solution at 319 K. ratio = Supnorting MatorialsCalculate the mass in grams of a double helical DNA molecule stretching from the earth to the moon (320,000 km). The mass of the double helix is about 1 x 10-8 g per 1000 nucleotide pairs and each base pair extends 0.34 nm. The human body contains about 0.5 g DNA. What can you say about the progression from double stranded DNA to chromosomes when you consider your answer to (a)?
- the length of a DNA double helix increases by 0.34 nm for everypair of nucleotides.The total number of nucleotides in a human body cell is 1.2 × 1010. Calculate the total length of double helix in a human body cellif this DNA has a molecular weight of 1.20 ×108 Dalton which contains a head in a about 200 nm long. Calculate the length of the DNA assuming the molecular weight of a nucleotide pair is 600 Dalton and assume that the DNA is a B-form and that there are 10 base pair per turn which makes is 34 Å per turn. ( 1nm = 10Å)The complementary strands of DNA in the double helixare held together by hydrogen bonds: G ≡ C or A = T.These bonds can be broken (denatured) in aqueous solutions by heating to yield two single strands of DNA(see Figure 1-13a). How would you expect the relativeamounts of GC versus AT base pairs in a DNA doublehelix to affect the amount of heat required to denatureit? How would you expect the length of a DNA doublehelix in base pairs to affect the amount of heat requiredto denature it?
- Assuming that the DNA codes for 20 amino acids, where each amino acid is coded by 3 nucleotides each. What is the length of the DNA if 1 turn made up of 10 nucleotide base pairs measures 34A?You are supplied with the following information about a DNA molecule: The molecular weight of a typical nucleotide is 660 Da. The linear density of double stranded DNA is 4 x 106 Da per micrometer. There are 10 base pairs in one complete turn of the double helix. Answer the following questions about a DNA molecule with a length of 3.3 micrometer and a base composition which contains 20% of the base adenine (A). (a) How many phosphor atoms are present in this DNA molecule?(b) How many full turns of the DNA helix are there in this molecule?(c) What is the percentage of guanine bases in the DNA molecule?(d) How many hydrogen bonds are there in the molecule?(e) How many phosphodiester bonds are there in the molecule?( f ) What is the length in basepairs of a DNA molecule that contains 606 full turns of the double helix?Assuming the average weight of a deoxynucleotide monophosphate (dNMP) is 327.0 g/mol, how many picomoles of DNA are present in 500ng of a 1000bp DNA fragment?