c. Propose a synthesis for the compound D shown below, starting with benzene. Identify appropriate reagents, reaction conditions and give the detailed mechanism for the formation of the azo bond. но -он Compound D

Q: (b) Which of the following halogenated compounds could be converted into a Grignard reagent? H,CO.…

A: The alkyl or aryl magnesium complexes are termed as the Grignard reagents and are represented as…

Q: A D H,O* CH,CI H,SO, H;C B E KMNO, + + HNO, H AICI, AICI, A Cl, FeCl, F+G 7. Based on the reaction…

A: (7) (a) Structures of compounds A to H are -

Q: (d) 3-Methylpyridine N-oxide reacts with nitric acid and sulfuric acid to produce compound (19).…

A: In organic chemistry, compounds usually follow addition, substitution, or elimination reaction. The…

Q: Propose a plausible mechanism for the following transformation. но to 1) H-CEC: Na 2) H20

A: When epoxide is treated with sodium acetylide (HCCNa) , then initially lone pair of oxigen of…

Q: 1. Give the expected Zaitsev and anti-Zaitsev products in the following reactions. Label the Zaitsev…

A: See both type of products in red boxes.

Q: A student tried to carry out the following reaction sequence, but none of diol A was formed. Explain…

A: The problem in the above reaction is that that the grignard reagent forms and alkoxide which is…

Q: 18. Suggest a plausible mechanism with structures of the following reaction: Br, H,0 CH3 CH2B.…

A: In the reaction mechanism of the above reaction, first the alkene will attack on the Br2 molecule as…

Q: Starting from ethane, provide a synthesis of the compound below showing all the reagents necessary…

A:

Q: (1)NANH2, NH3 (2) BrCH2сH3 QH

A: NaNH2 is a base which abstacts proton from alcohol and convert alcohol into alkoxide ion.  This…

Q: 4. Give a detailed mechanism for a reaction of ethylamine and acetyl chloride under basic…

A:

Q: Propose a plausible mechanism for the following transformation: معلی معلم OH H₂O* OH

A: H3O+ is hydronium ion. It is used as a catalyst in this reaction.

Q: 1. Provide a detailed mechanism for the following reaction and give the product. H2SO4

A: First c=O will attack on H+ and carbonyl carbon will protonate and then H2O will attack and…

Q: 3. When compound 11 is treated with two equivalents of methansulfonic acid (MSOH) in…

A: The reaction involves 2 molecules of 11 as reactant. The reaction mechanism is drawn below.

Q: 4. Propose a plausible mechanism for the Wittig reaction and then the enol ether hydrolysis. ( H,C-O…

A: Since, you have asking multiple questions, so I will solved first question for you. You can see…

Q: B3. Write a detailed mechanism for the following Knorr Synthesis 1) (BUO-NO (0.5 equiv) , HCI A…

A: Preparation of pyrrole compound by using beta amino keto-ester and beta-keto ester is called Knorr…

Q: H2NNH2 'NH R-N N-R NH cat. H+

A:

Q: a. Propose a synthesis for compound D shown below, starting with benzene. Identify appropriate…

A: Here we have to propose a synthesis of the given compound from starting material from benzene in…

Q: HO H;O, 0-10 °C OH 2.

A:

Q: Suggest a mechanism for the following reaction. Explain why NaB(CN)H3 is preferable to NABH4 as…

A: We have to suggest mechanism for the following reaction in step 2

Q: D. Provide reasonable mechanisms for the following reaction H NaOH, H₂O, A

A: Aldol condensation: The alpha hydrogen of carbonyl compounds is acidic in nature and it is removed…

Q: c) Write a detailed mechanism for the following transformation: OH CH;OH H,SO, (cat)

A:

Q: For the compound below, propose an efficient synthesis using diethyl malonate as a starting…

A: In this question, we will synthesized the given product by using diethyl malonate as a starting…

Q: ОН О MECN OMe OMe H2SO4 NHAC

A:

Q: Give the major product of each of the following reactions: Bra d. CH,C=CCH, CH,I, excess HBr e.…

A: According to Markonikov's addition, the more electronegative part goes to the more substituted C in…

Q: Imine and Enamine Mechanisms Provide a complete mechanism to account for the formation of the…

A:

Q: Write a detailed mechanism for this transformation. OH HCI НО НО H2O -OH

A:

Q: c) Outline a synthesis for compound G shown below starting with a 2- hydroxybenzylketone.

A:

Q: 3. The Mannich reaction can take many forms, including reactions where aromatic heterocycles are…

A: 1. Sn2 reaction between alkyl bromide and pyridine. Michael addition followed by Mannich reaction.

Q: Propose a mechanism for this isomerization. ARSO3H

A: Any molecule or ion which are electron-rich species is called nucleophile, for example -NH2,-OH, and…

Q: b. Provide mechanisms and/or products for the following transformations. Pd°Ln, Cul, PhBr 1. HBpin,…

A: 2 b. 1-Hexyne reacts HBpin produces borate. It is used in the suzuki coupling. 1-Hexyne reacts with…

Q: 3. Propose a mechanism for the following reaction sequence. Et 1. BuLi, 2 moles 2. CH3CH,Br Ph

A: Organic reaction:

Q: NaBH, H+ agua CH,OH H,0 H+ Ag,0 1) H+ 2) NH, OH-

A: In this question, we will draw the products for all reaction by using mechanism and intermediate…

Q: Provide a detailed mechanism for the following reactions and determine the major product: 14. a) b)…

A:

Q: N-acetyl-p-benzoquinone imine (NAPQI) is a toxic metabolite of acetaminophen that can lead to liver…

A: We have given the reaction between (N-acetyl-p-benzoquinone imine) (NAPQI) with Liver protein, in…

Q: Suggest a) OH Br OH b) с) O-CH3 HO

A:

Q: What is the configuration of the chiral center in the bromoepoxide? How do you account for the…

A: Step 1- Is a Fischer esterification to make diethyl malonate. Step 2-Protectionhydroxyl group in the…

Q: For the compound below, propose an efficient synthesis using diethyl as a starting material. Provide…

A:

Q: Propose an efficient synthesis for the transformation shown below. Provide explanations for each…

A:

Q: HCIO4 Br2 MECO2H

A: 1- In the first reaction, Keto form converted into enol form in acidic medium and then enol form is…

Q: Propose a plausible mechanism for the following transformation. HO 1) H-CEC: Na 2) H3Oʻ

A: The functional group is a key component that pertains to a molecule and it involves a characteristic…

Q: iv) NGÔM, HO Heat

A: Note : Retro aldol followed by intramolecular aldol condensation. (For mechanism, see below).

Q: 1. Answer ALL parts of this question. OH IN Ph Ph 1 Figure Q1 (a) Provide a two-step retrosynthetic…

A:

Q: Ph H₂SO4 Ph SO₂H Producto minoritario SO₂H Producto mayoritario

A:

Q: 3. Propose a mechanism for the following reaction sequence. Et 1. BuLi, 2 moles 2. CH3CH2Br Ph

A: The reaction proceeds with a nucleophilic addition elimination reaction mechanism at the carbonyl…

Q: b. Enolate chemistry facilitate many C-C bond-forming reactions, including Aldol reactions, Claisen…

A: Michael  addition

Q: For the following molecules, suggest two retrosynthesis pathways with their synthetic equivalents.…

A: Here we have prepare the following compounds by two retrosynthesis pathway

Q: Stork developed the tollowing enamine reaction as an alternative to the Robinson annulation. Below…

A:

Q: NGOH/H,O 4

A: Since you have asked multiple question, we will solve the first question for you as per our…

Q: HCI CH3-CH2-CEN CH3-CH2-C-OH + NH,CI H2O

A:

Reactions of Ethers

Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.

Epoxides

Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.

Williamson Ether Synthesis

An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.