Arrange the following in the order of decreasing reactivity towards a nucleophile (number them 1-5) Acid amiide Acid halide Ester Carboxylic acid Acid anhydride Rationalize the order of reactivity and explain why

Arrange the following in the order of decreasing reactivity towards a nucleophile (number them 1-5) Acid amiide Acid halide Ester Carboxylic acid Acid anhydride Rationalize the order of reactivity and explain why

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter17: Carboxylic Acids

Section: Chapter Questions

Problem 17.45P

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Concept explainers

Amines

Amines are organic compounds with a nitrogen atom having a lone pair of electrons on it. They are derived from ammonia (NH3) wherein hydrogen atoms are substituted by an aryl or alkyl group.

Question

Arrange the following in the order of decreasing reactivity towards a nucleophile (number them 1-5)

Acid amiide
Acid halide
Ester
Carboxylic acid
Acid anhydride

Rationalize the order of reactivity and explain why

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

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