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- explain why the protein binding of the drug is not correlated with the distribution or elimination parameters?What are the: a.)Active Ingredient Classification (ex. Analgesic) B.) Brand Names available in the market(ex. Biogesic) C.) Label claim (ex. 500 mg/tablet, 160 mg/5 mL).d.) Dosage forms available in the market (ex. tablet) and matter classification (ex. solid/liquid/gas – homogeneous/ heterogeneous E.)Dosage and regimen (ex. take #1 500 mg tablet every 4 hours) f.)Pharmacologic Use or Indication. of a precipitated sulfur or the one at the third row only?What is the corresponding schedule for each of these drugs? a. Codeine at concentration of 10mg/mL (oral liquid) b. Codeine at concentration of 2mg/mL (orgal liquide)
- ▪ A patient arrives at the ER complaining of seizures. The patient is taking phenytoin as prescribed which has a therapeutic range of 10-20 ug/mL. You order the SDC and find it is 8 ug/mL at steady state. This is an indication that A) dose needs to be increased. The dose needs to be individualized. ▪ B) The patient is noncompliant.For each of the following drugs, indicate whether the physiological effects of the drug were known before or after the target was identified. a. Penicillin b. Sildenafil (Viagra) c. Rofecoxib (Vioxx) d. Atorvastatin (Lipitor) e. Aspirin f. Indinavir (Crixivan).) How can these physiological factors listed below affect drug effect? Explain each. - diurnal rhythm - acid - base balance - hydration - electrolyte balance।
- Using conversion factors, solve each of the following clinicalproblems:a. A nurse practitioner prepares an injection of promethazine,an antihistamine used to treat allergic rhinitis. If thestock bottle is labeled 25 mg /mL and the order is a doseof 12.5 mg, how many milliliters will the nurse draw up inthe syringe?b. You are to give ampicillin 25 mg/kg to a child with a massof 62 lb. If stock on hand is 250 mg /capsule, how manycapsules should be given?Briefly explain this statement -"Therapeutic drug monitoring of Warfarin" Please explain at your own words(500-600 words appropriately).the number of connection forces between drug (s) and receptor is (R) (S) A.-- а. О O b. 4 С. 2 d. 3
- Briefly explain two (2) advantages of dapagliflozin for patients with cardiovascular diseaseThe order is for 0.35 mg of epinephrine stat; the drug is available as an ampule with the concentration labeled as 1:1000 (weight in grams: volume in mL). How much volume should be administered to the patient per dose? 1) 0.035 mL 2) 0.35 mL 3) 3.5 mL 4) 35 mLThe clinical effectiveness of a drug majorly depends on: a. Clearance b. Potency c. Affinity to receptors d. Half-life