1-chlorobutaneAlkyl Halides (R-X):1. In the table below provide the requested information about each alkyl chloride and rank themaccording to their predicted rates of reaction (1= fastest; 2= second fastest; etc.). If a compoundwill NOT react, write NR.Compound Name2-chlorobutanetert-butyl chlorideOHbile chM₂ CStructureJCICH3+ Ag X (ppt) + HNO 3Classification(1º, 2º, 3º,aryl)RankPredictedRate of SN2(1 = fastest;NR = no rxn)RankPredictedRate of SN1(1 = fastest;NR = no rxn)What structural feature did you look at to predict the rates? Explain why this structural feature affectsrates of substitution reactions.

Basic concepts of substitution reactions.

Alkyl Halides (R-X): 1. In the table below provide the requested information about each alkyl chloride and rank them according to their predicted rates of reaction (1= fastest; 2= second fastest; etc.). If a compound will NOT react, write NR. Compound Name 1-chlorobutane 2-chlorobutane tert-butyl chloride ₂ C- Structure + CI CI CH3 Classification (1º, 2º, 3º, aryl) Rank Predicted Rate of SN2 (1= fastest; NR= no rxn) Rank Predicted Rate of SN1 (1= fastest; NR= no rxn) What structural feature did you look at to predict the rates? Explain why this structural feature affect ates of substitution reactions.

Alkyl Halides (R-X): 1. In the table below provide the requested information about each alkyl chloride and rank them according to their predicted rates of reaction (1= fastest; 2= second fastest; etc.). If a compound will NOT react, write NR. Compound Name 1-chlorobutane 2-chlorobutane tert-butyl chloride ₂ C- Structure + CI CI CH3 Classification (1º, 2º, 3º, aryl) Rank Predicted Rate of SN2 (1= fastest; NR= no rxn) Rank Predicted Rate of SN1 (1= fastest; NR= no rxn) What structural feature did you look at to predict the rates? Explain why this structural feature affect ates of substitution reactions.

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter14: Elimination

Section: Chapter Questions

Problem 18E

See similar textbooks

Similar questions

The electrophilic addition of Br, to several alkenes was examined. Explain why the relative reaction rates are as follows: H. H H CH3 H CH3 H CH3 H3C CH3 < C H H H H3C H H3C CH3 H3C CH3 Increasing reaction rate with Br2
3. Propose a reasonable mechanism for the following cyclization reactions. Then classify the cyclization and identify if the product would be favored or disfavored based on Baldwin's Rules. O a. b. C. НО. Br Ph Ph OCH 3 OH nBuLi NaOH H₂O عليم H₂SO4 1
In each reaction box, place the best reagent and conditions from the list below он ... он 2) 3) HаCrOд Н2О2, NaOH, H20 Br2 Cl2, H20 PCI3 ВН- THF H2SO4 (conc.) dilute H3O* NaBH4 in EtOH
In each reaction box, place the best reagent and conditions from the list below. 1) 2) 3) 4) CHяCH-CH2CI, AIClk CH3COO NBS, ROOR, hv ВНз/THF CrO3, H2SO4 HЕг Н2О2, NaOH, H20 Br2, FeBr3 CHяCH-CI, AICIS Br2 (CH3)3CO Pd, H2 MCPBA Br2, H20
H3C-C O: H ethanal :CN: and the electrophile is cyanide ion In the step you have just written, the nucleophile is slow rate-determining Ö—0—1 H3C-C-C=N; adduct
1. Provide the product for each of the following reactions. a. b. С. d. Н.С. О H3C H3C CH3 Н3С CH3 H CH3 0 Н 1. EtLi 2. Н3О+ H3C O OH нсисH3OH HạC-NH, HCI
c. Snl reactions dominate under polar protic solvents. Increasing the polarity of the solvent will increase the rate of the reaction because the polar solvent will stabilize the dispersed charges on the transition state more than it will stabilize the neutral reactant. Label areas of ô* and & on the molecules of the transition state of the SN1 reaction below: Me Me Ме Me Me H20 Br -Br OH + НО \'H Et Et RDS Et H Et Et transition state not isolable carbocation intermediate not isolable
Q2. Classify the following reactions to: 1. Wagner- Meerwein rearrangement 2. Pinacolic Rearrangement 3. Beckmann Rearrangement 4. Baeyer-Villiger Rearrangement 5. Wolff Rearrangement H,SO4 1. OH OH Ag(I) 2. NO NO OH H,SO4 NH 3. OH H;C, H,SO, + H,O H 4. H;C CH, CH3 HO H,SO4 5. OH OH NH,OH H,SO4 NH 6. A
5. Predict the major product, which will be formed under the depicted reaction conditions. Be sure to indicate stereocher clearly when relevant. d. HN, pyr е. Nao (cat.) OEt НО f. HCI, H20 HCI, H20 Ph heat HCI, NH3 H. then NaCN
In each reaction box, place the best reagent and conditions from the list below. Br 1) Br 2) 3) 4) Br2, H20 PBr3 ВныTHF CH;CO0- (CH3);CO dilute H30* NABH4 H2CrO4 H2O2, NAOH, H2o
What is the missing reagent in the reaction below? of of. cr CI Multiple Choice O LIAIH4. [2] H2O (1] CH2=CHLI, [2] H2O (1]) (CH2=CH)2CULİ, (2) H20 (1] DIBAL-H, (2] H20
. Provide the reagents necessary to carry out the following conversion. OH u NaOH/H₂O 1. NaOCH3, 2. H₂O¹ 1. (CH₁) COK, 2. BH3, 3. H₂O/NaOH/H₂O | 1.(CH3)COK, 2. HO