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Which of the following is true of the absorption, distribution, and elimination of delta-9-tetrahydrocannabinol?
Question 11 options:
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When ingested, THC is quickly and efficiently absorbed, and more than 30 percent reaches the brain within 10 minutes |
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When smoked, the peak mood-altering and cardiovascular effects occur together, usually within 5-10 minutes |
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When smoked, THC is rapidly distributed first to the heart and then absorbed into the blood, reaching the brain and the rest of the body |
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When ingested, the peak mood-altering and cardiovascular effects occur between 40-60 minutes after ingesting |
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- Synthetic opioids are frequently being used for analgesia, i.e. as pain killers. While morphine or other full agonists such as fentanyl are the strongest pain killers available, partial agonists such as nalorphine or pentazocine are being used in applications requiring something intermediate in strength between morphine and basic painkillers such as aspirin. Considering a situation where both morphine and pentazocine are co-administered, select the TRUE statement(s): A. With increasing concentrations of pentazocine, the percent maximal response for morphine can be reduced to the level of pentazocine. B. The dose-response curve for morphine will shift to the right and its shape will not change (parallel rightward shift). C. The dose-response curve for morphine will shift to the left and its shape will not change (parallel leftward shift). D. The maximal efficacy of morphine alone can be exceeded. E. None of the answers here is correct. Please answer asap and type your answer and…What is the maximum allowable dosage of the most commonly used anesthetic solution i.e. 2% Lidocaine HCl with 1:100,000 epinephrine for a 52 kg healthy adult?What is the maximum allowable dosage of the most commonly used anesthetic solution i.e. 2% Lidocaine HCl with 1:100,000 epinephrine for a healthy adult?
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- Dexamethasone 1 Dexamethasone is a glucocorticoid administered as an anti-inflammatory agent and immunosuppressant. It is structurally similar to cortisol produced naturally by your adrenal glands. It treats a number of conditions including inflammation, arthritis, autoimmune conditions, skin and eye conditions, asthma, multiple sclerosis, blood or bone marrow disorders, different types of cancer (e.g. leukemia and lymphoma), and severe allergies. This medication is also administered to patients with severe COVID-19 symptoms to decrease mortality rates*. Given that it is a steroid, which family of macromolecules does dexamethasone belong to? *research from the University of Oxford, "Randomised Evaluation of COVID-19 Therapy" trial, recovery.net 2 Given the structures of dexamethasone (left) and cortisol (right) below, and that they both bind to the same receptor, would you expect the binding of dexamethasone to be to the active or allosteric site of the receptor? 3 Based on the…The catechol system is important for the binding of adrenergic agonists, yet is not required for adrenergic antagonists. Why should this be the case? The active enantiomer of arylpropanolamines is S, yet for the arylethanolamines it is R. What do you think is going on in the binding site? Summarize what a selective noradrenaline reuptake inhibitor does and how it would affect depression.To treat patients during the acute phase of opioid withdrawal, clinicians may use NSS-2 Bridge device, which is a small electrical nerve stimulator that is placed behind the person's ear and emits electrical pulses. True or False