A. What is the name of the specific sequence the scientists are measuring in the experiment shown below. B. For the individuals with lymphocyte pathology in the right panel, which gene is likely defective that causes the data shown? C. Explain why the length of the repeat sequence decreases with age.

Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter14: Dna Structure And Function
Section: Chapter Questions
Problem 37CTQ: An adult with a history of tanning has his genome sequenced. The beginning of a protein-coding...
icon
Related questions
icon
Concept explainers
Question

In the experiment summarized below, scientists were examining the presence of specific sequences in individuals with age. In this experiment they extracted DNA from lymphocytes of various aged individuals and measured the length of a TTAGGG (in kb) repeat they found in their genomic DNA (Left Panel). In the right panel, the scientists measured the length of the same repeats in individuals with lymphocyte failure (red dots most severely effected) that have a mutation in a critical enzyme. Answer the following questions in 2-3 sentences each.

A. What is the name of the specific sequence the scientists are measuring in the experiment shown below.

B. For the individuals with lymphocyte pathology in the right panel, which gene is likely defective that causes the data shown?

C. Explain why the length of the repeat sequence decreases with age.

C. Explain why the length of the repeat sequence decreases with age.
TTAGGG Repeat (kb)
16
14-
12
O
CO
2
n=414
n=418
0
0 10 20 30 40 50 60 70 80 90 100
16
14
12
10
8
6
4
2
n = 89
n=121
0
0 10 20 30 40 50 60 70 80 90 100
Age (yrs)
Transcribed Image Text:C. Explain why the length of the repeat sequence decreases with age. TTAGGG Repeat (kb) 16 14- 12 O CO 2 n=414 n=418 0 0 10 20 30 40 50 60 70 80 90 100 16 14 12 10 8 6 4 2 n = 89 n=121 0 0 10 20 30 40 50 60 70 80 90 100 Age (yrs)
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 3 steps

Blurred answer
Knowledge Booster
Cancer therapy
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax