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- Unanswered As a hobby you propagate a population of worms. You notice that one worm is now clear instead of being tan. You trace down the mutation and discover that it is a single basepair deletion in a pigmentation gene. Explain how a single basepair deletion could result in a drastic mutant phenotype. Your answer Write your response here... ion ongeneratio If a mutation is adaptive in one environment, it will be adaptive in 7 1 every environment. True False tounhness of aAchondroplasia is an autosomal dominant form of dwarfism caused by a single gene mutation. Calculate the mutation rate of this gene given the following data: 10 achondroplastic births to unaffected parents in 245,000 births.
- Mutation is NEVER NECESSARY for finding optimal solutions to a problem. True FalseWhich of the following statements regarding mutation is FALSE? Question options: mutations typically occur during the production or repair of DNA mutations involve changes in DNA sequence mutations in somatic cells of multicellular organisms are passed to offspring through sexual reproduction mutations may be due to mistakes in normal biological processes such as DNA replication mutations can be caused by certain environmental agents ALL of these statements are TRUE An alteration in the DNA sequence of a gene that alters the amino acid sequence of the encoded polypeptide but does NOT alter the function of this polypeptide is defined as a(n) ________ mutation. Question options: frameshift missense NONE of these terms accurately completes this sentence silent neutral nonsenseCan someone give me a few inherited disorders that are NOT caused by mutations? and if possible, please explain/name a gene that contributes to this disorder? Thank you!
- https://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=TP73 using the above linke, Briefly describe the most common mutation found in this gene. Include details about the type of mutation, and the predicted effect. . where does the mutation occur, what bases are changed; does the mutation change the protein sequence, and if so what would the likely biologics consequences be?Explain the difference between a gain-of-functionmutation and a dominant-negative mutation. Why areboth these types of mutation usually dominant?Match each example of mutation to the correct effect on function. Hypomorphic mutation Hypermorphic mutation Antimorphic mutation Neomorphic A deletion results in the loss of part of a protein and the protein retains some of its normal activity. A mutant allele makes a protein with increased cataytic activity. A mutant form of a transcription factor binds new DNA sequences to activate different genes. A mutant from of a receptor protein interferes with the function of the wild-type receptor through heterodimerization.
- Select any one type of genetic mutation and explain it with the help of related Disorder?. The physicist Stephen Hawking, famous for his theories about black holes, has lived past the age of 70 withamyotrophic lateral sclerosis (ALS), a paralyzing neurodegenerative disease that is usually fatal at a muchyounger age. Recently, geneticists discovered that amajor cause of ALS is the unusual expansion of ahexanucleotide repeat (5′-GGGGCC-3′) that lieswithin a gene called C9ORF72, at a location outside ofthe gene’s open reading frame (ORF). A single expanded allele is sufficient to cause ALS, but the reasonthe disease allele is dominant remains unclear. Someexperimental results support the theory that the allelemakes a toxic RNA containing the expanded repeat. Ifthis theory is correct, in what ways is the mutant ALScausing allele similar to the mutant allele that causesHuntington disease? In what ways is it similar to themutant allele that causes fragile X syndrome?Cystic fibrosis is caused by a mutation in a gene resulting in changes to a protein that regulates the movement of salt in and out of cells. The result is thick, sticky mucus in the respiratory, digestive and reproductive systems. Which application of genetic engineering is a promising treatment for cystic fibrosis? O Gene therapy. DNA recombination. OGel electrophoresis. DNA fingerprinting.