A reaction mixture spotted on the TLC plate has been refluxing for one hour. There is a single organic product of the reaction. After 1 hour a student elutes a TLC plate of the starting material(s) (SM), the known product (P) and the reaction mixture (RM). Based on the TLC below, do you think the reaction should be refluxed further? Explain your answer. SM+ P- RM+ O O о

A reaction mixture spotted on the TLC plate has been refluxing for one hour. There is a single organic product of the reaction. After 1 hour a student elutes a TLC plate of the starting material(s) (SM), the known product (P) and the reaction mixture (RM). Based on the TLC below, do you think the reaction should be refluxed further? Explain your answer. SM+ P- RM+ O O о

Principles of Instrumental Analysis

7th Edition

ISBN:9781305577213

Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Chapter31: Thermal Methods

Section: Chapter Questions

Problem 31.8QAP

See similar textbooks

Similar questions

A TLC plate was run in cyclohexane:ethyl acetate 4:1, the pure product, 2 starting materials and final product were spotted. what does the tlc tell you about the product.
An unretained solute is eluted from a GC column in 1.80 min. Decane (C10H22) is eluted in 15.63 min and undecan (C11H24) is eluted in 17.22 min. What is the retention time (report to 2 decimal places, in minutes) of a compound whose retention index is 1050?
Concentrated sulfuric acid, H2SO4, was used to visualize the sugars (cellobiose and glucose), whose identities were confirmed by TLC. Describe the mechanism by which the sulfuric acid, H2SO4, produces visible spots where sugars are present on the TLC plate
A second spectrophotometric method for the quantitative analysis of Pb2+ in blood yields an Ssamp of 0.712 for a 5.00 mL sample of blood. After spiking the blood sample with 5.00 μL of a 1560 ppb Pb2+ external standard, an Sspike of 1.546 is measured. What is the concentration of Pb2+ in the original sample of blood?
4- A sample containing H2C204 had a purity equal to 90.50% (w/w). An unknown mass of this sample was dissolved in water and transferred to a 50.00 mL flask. An aliquot of 25.00 mL was transferred to an erlenmeyer flask and 50.00 mL of a 0.2000 mol L^-1 NaOH solution were added. %3 Excess NaOH was titrated with 0.09000 mol L^-1 HCI solution using 2.000 mL. Calculate the mass (g) of the sample used. Data: H = 1.008 C= 12.01 O = 16.00
Consider a separation performed on a 30.0 mm long open tubular column with a 0.50 mm diameter and a 2.0 µm thick stationary phase. Compound A eluted at 12.63 min, compound B eluted at 13.24 min, and the unretained solvent eluted at 1.205 min. What are the adjusted retention times, t, and retention factors, k, for compounds A and B? TRA KA = || TRB = KB = = min min
A mixture of benzene, toluene, and methane was injected into a gas chromatograph. Methane gave a sharp spike in 42 s, whereas benzene required 251 s and toluene was eluted in 333 s. Find the adjusted retention time and retention factor for each solute.
A 10.00 mL of natural water sample containing Ni2+ was pipetted into a volumetric flask and diluted to 50.00 mL with pure water. In the second 10.00 mL of natural water sample transferred into a volumetric flask, exactly 4.00 mL of a Ni2+ solution with a concentration of 5.99 mg/L was added and then diluted to 50.00 mL with pure water. The measured absorbance is A1= 0.436 and A2 = 0.663. What is the Ni2+ concentration in unit of mg/L in the natural water sample?
Based on TLC, how can you tell if the reaction is complete and what is the relevvance of the multiple marks in the lanes of the tlc? PROCEDURE To a six inch test tube was added thiamine hydrochloride (0.65 g), followed by water (2mL). The mixture was gently shaken until homogeneous, and then ethanol (7.5 mL)was added. Finally, sodium hydroxide (10%, 1.5 mL) was added and the mixture wasgently stirred to ensure complete mixing.Benzaldehyde (3.8 mL) was then added at room temperature in one portion with gentlestirring. The pH of the resulting reaction mixture was determined and adjusted to >10by dropwise addition of 10% sodium hydroxide. The reaction mixture was then partiallysubmerged in a 65 °C water bath2 and the progress of the reaction was periodicallymonitored by TLC analysis.Once TLC analysis indicated that the reaction was complete, the reaction mixture wascooled to approximately room temperature, and then chilled in an ice-water bath. Theresulting precipitate was collected by…
In your General Chemistry Lab, you and your partner inject a mixture of the three molecules shown below (all isomers of C7H14) into a Gas Chromatograph. Choose the correct elution order for these molecules, from smallest retention time to largest, from the given choices. A В A
Chrome → C esc File Edit View History Aktiv Chemistry OH ! 1 app.101edu.co Q oxidation 2 W Bookmarks Profiles Tab Window Help X + 1,503 # Below is a TLC of the oxidation of cyclohexanol to cyclohexanone. Based on the TLC plate, which of the following statements would be true about the progress of the reaction? (SM starting material; R = reaction mixture) 3 -t-t-t-t SM R 11 $ 4 JUN 30 % 5 ERT 121 6 MacBook Pro & PACES 7 W Y U O A) All of the starting material has been converted to product. 8 B) None of the starting material has been converted to product. 1 8 15% 9 C) The reaction solution is a mixture of starting material and product. D) The TLC does not provide any information on the reaction. 2 0 Thu 8:08 PM 0 K Paused P { : ( Up } ]
What is Ultra-Performance Liquid Chromatography (UPLC)? What are the differences and advantages of UPLC over HPLC?