Q2The following Diels-Alder reactions have been used in industrial syntheses of pharmaceuticalagents. Suggest structures for the products A -E and briefly explain your reasoning.a)ACHCO2H, 20 °Сb)BMcoH3COToluene, 120 °Cc)Lewis acid catalystOCH3+ D'BuOCH2CI2, -78 °Cmajorminord)PHCH20.EXylene, 150 °C

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Answered: a) A CH3CO2H, 20 °c b) В H3CO Toluene,…

Chemistry

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Chapter1: Chemical Foundations

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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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2) Predict the major product for each Diels-Alder reaction. Include stereochemistry where appropriate. H. C=N (a) H H. CH3 CH;O, (b) Ph (c) Ph
b) Which of these dienophiles gives the FASTEST reaction with cyclopentadiene? CH2 CH2 A. | В. C. | D. | Give structures for the major Diels-Alder product of the following reactions: 1,3- cyclohexadiene and tetrachloroethene 1,3-cylcohexadiene and fumaric acid, the trans isomer of maleic acid с.
(a) Complete the following sequence of reactions (i.e., give the structure for compounds A and B), giving structural details of all key intermediates. heat & A COOCH3 H₁₂ Ni (b) Provide the bond line structures for the pair of compounds used for the Diels-Alder synthesis of the compound shown below. O B COOCH3 (c) Draw the two major products obtained when (3E,5Z)-2,2,3,6,7-pentamethylocta-3,5-diene reacts with HBr at low and high temperatures. Label the products as the kinetic or thermodynamic product AND, if applicable, use dashes and wedges to show the correct stereochemistry in the obtained products.
3. The following reactions are not technically the Diels-Alder reaction, but you should still be able to predict the product (with appropriate regio/stereochemistry). (a) (b) OMe OMe H3C N + NC H3C. CN CH3
3) Predict the major product for each Diels-Alder reaction. Include stereochemistry where appropriate. ÇOOCH, (а) + CH;O H OCH, (b) CH,O. СНО (c)
4) Identify the reagents to prepare the following compound via Diels-Alder reaction Coalf DI Caotl a) X + .wolt •Looft b) x + you to c) of + Xco coot الاك d) None
Please help with 4c, 4d, and 4e. We havent learned kaw of equivalents so please do 4c a different way. thank you
The first step in a synthesis of dodecahedrane involves a Diels-Alder reaction between the cyclopentadiene derivative (1) and dimethyl acetylenedicarboxylate (2). Show how these two molecules react to form the dodecahedrane synthetic intermediate (3). + CH,0OCC=CCOOCH, COOCH ČOOCH3 Cyclopentadienyl- cyclopentadiene (1) Dimethyl acetylene- dicarboxylate (2) (3)
21. (a) Predict the product of the following Diels-Alder reaction( Show the correct stereochemistry for the product). cyclopentadiene + cis 1,2-dicyanoethylene (NC-CH=CH-CN) -------> (b) Show the mechanism for the reaction in(a) above.
(a) Tsomane and Nyiko were given a task of synthesising methylenecyclohexane 2. After a brief discussion with each other, Tsomane proposed Method A to synthesise 2 from cyclohexanone 1 while Nyiko proposed Method B that started from hydroxymethylcyclohexane 3. Each student believed that their proposed method is better than the other. (Scheme below) Ph THF A Ph Ph B H₂SO4 100 °C 3 OH (iii) In analysing both these methods, are there other possible alkene products other than methylenecyclohexane 2? Use mechanistic details to support your answer.
1. There are several isomeric alkanes of molecular formula C6H14.Two of these exhibit the following 1H-NMR spectra. Propose a structure for each of the isomers. Isomer A: δ = 0.84 (d, 12 H), 1.39 (septet, 2H) ppm Isomer B: δ = 0.84 (t, 3 H), 0.86 (s, 9H), 1.22 (q, 2H) ppm
Define Protons on Benzene Rings ?

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a) A CH3CO2H, 20 °c b) В H3CO Toluene, 120 °C Lewis acid catalyst "o c) OCH3 + D "BuO CH2CI2, -78 °C major minor d) PHCH20. E Xylene, 150 °C