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- When phosgene is treated with excess methanol, a product is formed whose "H NMR spectrum shows one peak-a singlet at 3.8 ppm. Provide a complete, CH,OH ? CI CI detailed mechanism for this reaction. Phosgene2. Draw a plausible mechanism for the following transformation: [H₂SO4] excess EtOH -H₂O EtO OEtWhat is the product of the following sequence of reactions? D | NaOH NaNH2 H3O+ || ||| explain each steps..explanation needed. don't give Handwritten answer IV NH₂
- 3. Propose a plausible mechanism for the following transformation: & Q & CF3 H₂N CN 'N CF HOHReaction of 2° alcohol A with HCl forms three alkyl chlorides, all of whichresult from rearrangement of the 2° carbocation initially formed. Draw thestructures of these products and a mechanism that illustrates how eachis formed.3. Provide a mechanism for the following reaction. OMe a) MeLi (2 equiv) b) H3O+ HO Me Me
- When treated with NaOH, the bromide below gives an alkene by the E2 mechanism, by eliminationof the circled atoms: (a) Draw the Newman projection from which elimination takes place. (b) Draw the mechanism. (c) Draw the product with the proper stereochemistry. (d) Assign the proper stereochemical descriptor to the product. (Z, E? Trans,CiS?) (e)What would happen to the stereochemistry of the product if the enantiomer of the starting material were used inthe reaction?Propose a synthesis of molecule B from molecule A. For each step, indicate the necessary reagents.Provide major product and a mechanism for each below