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- Summarize the relationship between pKa and acid strength by completing the following sentences: a. The higher the pKa of an acid, the stronger or weaker the acid. b. The lower the pKa of an acid, the stronger or weaker the acid.Rank the following in order of increasing basicity. соо coo" coo .coo2）Rank the following in order of basicity and explain your choices.
- 1. c) Indicate the most acidic hydrogen in each of the following molecules. 요 CH3COCH 3 X° (CH₂CH₂)₂NLi O || CH3CNHCH3 CH,CH,ONa 4 d) Arrange the following bases in order of increasing basicity, starting from the weakest base on the left to the strongest base on the right. O (CH3)3CCCH3 (CH3), COK CHỊCH Li (CH₂CH₂),NPhysostigmine is used in the treatment of glaucoma. Within this structure, the atom indicated by is most basic, while atom is least basic. 1 H3C 2 CH3 3 NHCH3 4 2 (most basic), 4 (least basic) 1 (most basic), 4 (least basic) 2 (most basic), 3 (least basic) 1 (most basic), 3 (least basic) None of the above8. Rank each of the following in order of most basic (1) to least basic (4). Explain the reasoning for your answer. H3C CH2 H3C 8. H,C CH3 D
- Which is the strongest acid? O CH3CH₂CH₂CHFCH₂CO₂H OCH3CHBrCH₂CH₂CH₂CO₂H () CH,CH,CH,CBICH,CO,H CH3CH₂CH₂CF₂CH₂CO₂HProvide the approximate pKa of the following and circle the most acidic hydrogen.a. CH3CH2NH2b. CH3C≡CHc. CH2CH2d. CH3CH2OHRank the following compounds in order of decreasing basicity, putting the most basic compound first. NH₂ A. || > | > ||| > IV B. | > | > ||| > IV C. | > ||| > | > IV D. IV> | > ||| > | NH₂ Br III NH₂ F3C IV NH₂
- Rank the following compounds from the least basic to the most basicExplain why the C-H, bond is much more acidic than the C-H, bond in pentan-2-one. Select the single best answer. HH. perfar 0H, is more acidic than H, because loss of H, forms a resonance-stabilized conjugate base. H, is less acidic than H, because loss of H, forms a resonance-stabilized conjugate base. H, is more acidic than H, because loss of H, forms a resonance-stabilized conjugate base. a. H, is less acidic than H, because loss of H, forms a resonance-sta bilized conjugate base.4- Circle the strongest base. a) CH3O 6 CH3NH2 b) Clo I c) CH3CO or CF3CO2