4. One of the fungicides used in ornamental plants, trees, tomatoes and others is called fenarimol, which acts by inhibiting the synthesis of steroids in fungi. The synthesis of this fungicide starts from the reaction of a diaryl ketone with an organolithium derived from an exchange of the halogenate for the metal. Propose the synthesis starting from the halogenated precursor. (Do not forget to make the reaction mechanism in the formation of fenarimol).

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter19: Enolate Anions And Enamines
Section: Chapter Questions
Problem 19.40P: Enamines normally react with methyl iodide to give two products: one arising from alkylation at...
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4. One of the fungicides used in ornamental plants, trees, tomatoes and others is called fenarimol,
which acts by inhibiting the synthesis of steroids in fungi. The synthesis of this fungicide starts from
the reaction of a diaryl ketone with an organolithium derived from an exchange of the halogenate
for the metal. Propose the synthesis starting from the halogenated precursor. (Do not forget to
make the reaction mechanism in the formation of fenarimol).
CI
.CI
Br
N
HO
Fenarimol
Transcribed Image Text:4. One of the fungicides used in ornamental plants, trees, tomatoes and others is called fenarimol, which acts by inhibiting the synthesis of steroids in fungi. The synthesis of this fungicide starts from the reaction of a diaryl ketone with an organolithium derived from an exchange of the halogenate for the metal. Propose the synthesis starting from the halogenated precursor. (Do not forget to make the reaction mechanism in the formation of fenarimol). CI .CI Br N HO Fenarimol
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